RegulonDB RegulonDB 10.8: Operon Form
   

panBC operon and associated TUs in Escherichia coli K-12 genome


Transcription unit       
Name: panBC
Gene(s): panC, panB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] Jones CE., et al., 1993
[2] Merkel WK., et al., 1996
[3] Vallari DS., et al., 1985
Promoter
Name: panBp
+1: 149630
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 29
Sequence: tggcagtgctgctacggataaatcattgcccccaccaatgtgactgataaaatgccagacAgcacaacatcaatttatcag
                          -35                   -10         +1                   
Note(s): We assigned a putative transcriptional start site to this promoter based on the observation that the majority of the promoters, whose transcriptional start sites were determined experimentally, present a distance of 6 nucleotides between the transcriptional start site and the -10 box 3550697.
Evidence: [HIPP]
[RS-EPT-CBR]
Reference(s): [1] Jones CE., et al., 1993
[4] Salgado H, et al., 2012


Evidence    

 [HIPP] Human inference of promoter position

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Jones CE., Brook JM., Buck D., Abell C., Smith AG., 1993, Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase, and overexpression of the enzyme., J Bacteriol 175(7):2125-30

 [2] Merkel WK., Nichols BP., 1996, Characterization and sequence of the Escherichia coli panBCD gene cluster., FEMS Microbiol Lett 143(2-3):247-52

 [3] Vallari DS., Rock CO., 1985, Isolation and characterization of Escherichia coli pantothenate permease (panF) mutants., J Bacteriol 164(1):136-42

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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