Name: |
glpABC |
Synonym(s): |
OP00037 |
Gene(s): |
glpA, glpB, glpC
Genome Browser
M3D Gene expression
COLOMBOS
|
Note(s): |
The glpABC operon is upregulated by long-term (8 to 12 h) exposure of E. coli to some biocides Merchel Piovesan Pereira B, Wang X, Tagkopoulos I,2020. The transcript of glpABC is decreased after σE induction, as observed in high-throughput analysis of gene expression Lacoux C,2020. |
Evidence: |
[BTEI] Boundaries of transcription experimentally identified [PM] Polar mutation |
Reference(s): |
[1] Cole ST., et al., 1988 [2] Ehrmann M., et al., 1987 [3] Larson TJ., et al., 1992
|
Promoter |
|
Name: |
glpABCp |
+1: |
2352583 |
Sigma Factor: |
Sigma70 Sigmulon |
Distance from start of the gene: |
64
|
Sequence: |
aatgttcaaaatgacgcatgaaatcacgtttcactttcgaattatgagcgaatatgcgcgAaatcaaacaattcatgtttt -35 -10 +1
|
Evidence: |
[HIPP] [ICWHO]
|
Reference(s): |
[4] Huerta AM., et al., 2003 [3] Larson TJ., et al., 1992 [5] Yang B., et al., 1997
|
Terminator(s) |
|
Type: |
rho-independent |
Sequence: |
ctcctttctgATGCCCGGTAAGCATGTGGTTACCGGGCATttttgcgtac |
Reference(s): |
[1] Cole ST., et al., 1988
|
Type |
Transcription factor |
Function |
Promoter |
Binding Sites |
Growth Conditions |
Evidence (Confirmed, Strong, Weak) |
Reference(s) |
LeftPos |
RightPos |
Central Rel-Pos |
Sequence |
proximal |
CRP-cyclic-AMP
|
activator |
glpABCp |
2352482
|
2352503
|
-90.5
|
ttcataaattAAATGTGAATTGCCGCACACATtattaaataa |
nd
|
[GEA], [AIBSCS], [APIORCISFBSCS], [BPP]
|
[3], [7], [8]
|
proximal |
CRP-cyclic-AMP
|
activator |
glpABCp |
2352532
|
2352553
|
-40.5
|
aaatgttcaaAATGACGCATGAAATCACGTTTcactttcgaa |
nd
|
[GEA], [APIORCISFBSCS], [BPP]
|
[3], [7]
|
proximal |
CRP-cyclic-AMP
|
activator |
glpABCp |
2352572
|
2352593
|
-0.5
|
aattatgagcGAATATGCGCGAAATCAAACAAttcatgtttt |
nd
|
[GEA], [APIORCISFBSCS], [BPP]
|
[3], [7]
|
Type |
Transcription factor |
Function |
Promoter |
Binding Sites |
Growth Conditions |
Evidence (Confirmed, Strong, Weak) |
Reference(s) |
LeftPos |
RightPos |
Central Rel-Pos |
Sequence |
remote |
Fis
|
activator |
glpABCp |
2352396
|
2352410
|
-180.0
|
gtggcccgtgGTCTTATTTATGATTaacagcctga |
nd
|
[GEA], [AIBSCS]
|
[6]
|
remote |
Fis
|
activator |
glpABCp |
2352460
|
2352474
|
-116.0
|
ttgccgcgatGTTAAGAAAACATTCataaattaaa |
nd
|
[GEA], [AIBSCS]
|
[6]
|
proximal |
Fis
|
activator |
glpABCp |
2352508
|
2352522
|
-68.0
|
acacattattAAATAAGATTTACAAaatgttcaaa |
nd
|
[GEA], [AIBSCS]
|
[6]
|
proximal |
Fis
|
activator |
glpABCp |
2352515
|
2352529
|
-61.0
|
attaaataagATTTACAAAATGTTCaaaatgacgc |
nd
|
[GEA], [AIBSCS]
|
[6]
|
proximal |
Fis
|
activator |
glpABCp |
2352557
|
2352571
|
-19.0
|
cacgtttcacTTTCGAATTATGAGCgaatatgcgc |
nd
|
[GEA], [AIBSCS]
|
[6]
|
remote |
Fis
|
activator |
glpABCp |
2352610
|
2352624
|
35.0
|
tttttactatGGCTAAATGGTAAAAaacgaacttc |
nd
|
[GEA], [AIBSCS]
|
[6]
|
Type |
Transcription factor |
Function |
Promoter |
Binding Sites |
Growth Conditions |
Evidence (Confirmed, Strong, Weak) |
Reference(s) |
LeftPos |
RightPos |
Central Rel-Pos |
Sequence |
proximal |
GlpR
|
repressor |
glpABCp |
2352483
|
2352502
|
-90.5
|
tcataaattaAATGTGAATTGCCGCACACAttattaaata |
nd
|
[APIORCISFBSCS], [BPP], [SM]
|
[3]
|
proximal |
GlpR
|
repressor |
glpABCp |
2352523
|
2352542
|
-50.5
|
agatttacaaAATGTTCAAAATGACGCATGaaatcacgtt |
nd
|
[APIORCISFBSCS], [BPP], [SM]
|
[3]
|
proximal |
GlpR
|
repressor |
glpABCp |
2352555
|
2352574
|
-18.5
|
atcacgtttcACTTTCGAATTATGAGCGAAtatgcgcgaa |
nd
|
[APIORCISFBSCS], [BPP], [SM]
|
[3]
|
proximal |
GlpR
|
repressor |
glpABCp |
2352574
|
2352593
|
1.5
|
ttatgagcgaATATGCGCGAAATCAAACAAttcatgtttt |
nd
|
[APIORCISFBSCS], [BPP], [SM]
|
[3]
|
remote |
GlpR
|
repressor |
glpABCp |
2352614
|
2352633
|
41.5
|
tactatggctAAATGGTAAAAAACGAACTTcagagggata |
nd
|
[APIORCISFBSCS], [BPP], [SM]
|
[3]
|
Transcription factor |
Function |
Promoter |
Binding Sites |
Evidence (Confirmed, Strong, Weak) |
Reference(s) |
LeftPos |
RightPos |
Central Rel-Pos |
Sequence |
Fis |
activator |
glpABCp |
2352396
|
2352410
|
-180.0
|
gtggcccgtgGTCTTATTTATGATTaacagcctga
|
[GEA]
|
[6]
|
Fis |
activator |
glpABCp |
2352460
|
2352474
|
-116.0
|
ttgccgcgatGTTAAGAAAACATTCataaattaaa
|
[GEA]
|
[6]
|
CRP-cyclic-AMP |
activator |
glpABCp |
2352482
|
2352503
|
-90.5
|
ttcataaattAAATGTGAATTGCCGCACACATtattaaataa
|
[GEA]
|
[3], [7], [8]
|
GlpR |
repressor |
glpABCp |
2352483
|
2352502
|
-90.5
|
tcataaattaAATGTGAATTGCCGCACACAttattaaata
|
nd
|
[3]
|
Fis |
activator |
glpABCp |
2352508
|
2352522
|
-68.0
|
acacattattAAATAAGATTTACAAaatgttcaaa
|
[GEA]
|
[6]
|
Fis |
activator |
glpABCp |
2352515
|
2352529
|
-61.0
|
attaaataagATTTACAAAATGTTCaaaatgacgc
|
[GEA]
|
[6]
|
GlpR |
repressor |
glpABCp |
2352523
|
2352542
|
-50.5
|
agatttacaaAATGTTCAAAATGACGCATGaaatcacgtt
|
nd
|
[3]
|
CRP-cyclic-AMP |
activator |
glpABCp |
2352532
|
2352553
|
-40.5
|
aaatgttcaaAATGACGCATGAAATCACGTTTcactttcgaa
|
[GEA]
|
[3], [7]
|
FNR |
activator |
glpABCp |
2352536
|
2352549
|
-40.5
|
gttcaaaatgACGCATGAAATCACgtttcacttt
|
[GEA]
|
[9], [10]
|
Fis |
activator |
glpABCp |
2352557
|
2352571
|
-19.0
|
cacgtttcacTTTCGAATTATGAGCgaatatgcgc
|
[GEA]
|
[6]
|
GlpR |
repressor |
glpABCp |
2352555
|
2352574
|
-18.5
|
atcacgtttcACTTTCGAATTATGAGCGAAtatgcgcgaa
|
nd
|
[3]
|
CRP-cyclic-AMP |
activator |
glpABCp |
2352572
|
2352593
|
-0.5
|
aattatgagcGAATATGCGCGAAATCAAACAAttcatgtttt
|
[GEA]
|
[3], [7]
|
FNR |
activator |
glpABCp |
2352576
|
2352589
|
-0.5
|
atgagcgaatATGCGCGAAATCAAacaattcatg
|
[GEA]
|
[9], [10]
|
GlpR |
repressor |
glpABCp |
2352574
|
2352593
|
1.5
|
ttatgagcgaATATGCGCGAAATCAAACAAttcatgtttt
|
nd
|
[3]
|
Fis |
activator |
glpABCp |
2352610
|
2352624
|
35.0
|
tttttactatGGCTAAATGGTAAAAaacgaacttc
|
[GEA]
|
[6]
|
GlpR |
repressor |
glpABCp |
2352614
|
2352633
|
41.5
|
tactatggctAAATGGTAAAAAACGAACTTcagagggata
|
nd
|
[3]
|
FlhDC |
activator |
glpABCp |
nd
|
nd
|
nd
|
nd
|
[GEA]
|
[11]
|
ArcA-phosphorylated |
repressor |
glpABCp |
nd
|
nd
|
nd
|
nd
|
[GEA]
|
[9]
|