RegulonDB RegulonDB 11.0: Operon Form
   

sulA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: sulA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: sulA
Synonym(s): OP00092
Gene(s): sulA   Genome Browser M3D Gene expression COLOMBOS
Promoter
Name: sulAp
+1: 1020947
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 28
Sequence: cgaggctctttccgaaaatagggttgatctttgttgtcactggatgtactgtacatccatAcagtaactcacaggggctgg
                        -35                    -10          +1                   
Evidence: [CV(RPF/TIM)]
[HIPP]
[HTTIM]
[ICWHO]
[IHBCE]
[RPF]
[TIM]
Reference(s): [1] Cole ST. 1983
[2] Huerta AM., et al., 2003
[3] Maciag A., et al., 2011
TF binding sites (TFBSs)
[LexA,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal LexA repressor sulAp 1020942 1020961 -5.0 tcactggatgTACTGTACATCCATACAGTAactcacaggg nd [BCE] nd
[RcdA,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote RcdA repressor sulAp 1020896 1020906 47.5 tacacttcagGCTATGCACATcgttcttcgt nd [GEA], [APIORCISFBSCS], [BPP] [4]
remote RcdA repressor sulAp 1020910 1020920 33.5 ctggattgatTATGTACACTTcaggctatgc nd [GEA], [APIORCISFBSCS], [BPP] [4]


Evidence    

 [CV(RPF/TIM)] cross validation(RPF/TIM)

 [HIPP] Human inference of promoter position

 [HTTIM] High-throughput transcription initiation mapping

 [ICWHO] Inferred computationally without human oversight

 [IHBCE] Inferred by a human based on computational evidence

 [RPF] RNA polymerase footprinting

 [TIM] Transcription initiation mapping

 [BCE] Binding of cellular extracts

 [GEA] Gene expression analysis

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [BPP] Binding of purified proteins


Reference(s)    

 [1] Cole ST., 1983, Characterisation of the promoter for the LexA regulated sulA gene of Escherichia coli., Mol Gen Genet 189(3):400-4

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Maciag A., Peano C., Pietrelli A., Egli T., De Bellis G., Landini P., 2011, In vitro transcription profiling of the σS subunit of bacterial RNA polymerase: re-definition of the σS regulon and identification of σS-specific promoter sequence elements., Nucleic Acids Res 39(13):5338-55

 [4] Shimada T., Katayama Y., Kawakita S., Ogasawara H., Nakano M., Yamamoto K., Ishihama A., 2012, A novel regulator RcdA of the csgD gene encoding the master regulator of biofilm formation in Escherichia coli., Microbiologyopen 1(4):381-94

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