RegulonDB RegulonDB 10.7: Operon Form
   

cysB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: cysB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: cysB
Synonym(s): OP00105, cysGB
Gene(s): cysB   Genome Browser M3D Gene expression COLOMBOS
Note(s): cysB expression is inhibited by oleanolic and ursolic acid, which in turn affect the expression of the cysteine regulon and the stress response |CITS:[21221969]|.
Reference(s): [1] Bielinska A., et al., 1986
[2] Hryniewicz MM., et al., 1994
Promoter
Name: cysBp
+1: 1333788
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 67
Sequence: atacactaaggctataaatgatatagtggttatagttagcaccttttttattattaaatcGtattagtcacccgccaggtg
                          -35                    -10        +1                   
Evidence: [HIPP]
Reference(s): [3] Ostrowski J., et al., 1987
Terminator(s)
Type: rho-independent
Sequence: tgcgttatttTCGGCACCTTTTATGTAGCGAAGGTGCCGGaatatattct
Reference(s): [3] Ostrowski J., et al., 1987
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CysB repressor cysBp 1333751 1333797 -14.0 ataaatgataTAGTGGTTATAGTTAGCACCTTTTTTATTATTAAATCGTATTAGTCAcccgccaggt nd [APIORCISFBSCS] [5], [6]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal PhoP-Phosphorylated activator cysBp 1333734 1333757 -43.0 acctatacacTAAGGCTATAAATGATATAGTGGTtatagttagc nd [AIBSCS], [APIORCISFBSCS] [4]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: forward
Evidence: [ICA] Inferred by computational analysis
Reference(s): [7] Merino E, et al., 2005
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -19.4 1333674 1333703 tttataaacaAAGGGTCGCGAAAGCGGCCCTTTTTTATTgcatattatt
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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