RegulonDB RegulonDB 10.7: Operon Form
   

fucPIKUR operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: fucPIKUR
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: fucPIKUR
Synonym(s): OP00171, fucPIK
Gene(s): fucP, fucI, fucK, fucU, fucR   Genome Browser M3D Gene expression COLOMBOS
Reference(s): [1] Chen YM., et al., 1989
Promoter
Name: fucPp
+1: 2934119
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 116
Sequence: ctagctaataagtgtgaccgccgtcatattacagagcgttttttatttgaaaatgaatccAtgagttcatttcagacaggc
                       -35                  -10             +1                   
Evidence: [NAS]
Reference(s): [2] Podolny V., et al., 1999
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP1 activator fucPp 2934028 2934049 -80.5 tttcgattatTAAAGTGATGGTAGTCACATAAagtcaccttc nd [AIBSCS], [BPP], [GEA] [2], [3]
proximal CRP-cAMP2 activator fucPp 2934068 2934089 -40.5 tctagctaatAAGTGTGACCGCCGTCATATTAcagagcgttt nd [BPP], [GEA], [SM] [2], [4]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd FucR-L-fuculose-1-P activator fucPp nd nd nd nd nd [GEA] [2], [4]
Note(s): 1In the intergenic regulatory region the fucPIK and fucAO operons, there exist other potential CRP-binding sites, which are located at positions -80.5, -289.5, -297.5, and -387.5 relative to the transcription start site.
2In the intergenic regulatory region the fucPIK and fucAO operons, there exist other potential CRP-binding sites, which are located at positions -80.5, -289.5, -297.5, and -387.5 relative to the transcription start site.1In the intergenic regulatory region the fucPIK and fucAO operons, there exist other potential CRP-binding sites, which are located at positions -80.5, -289.5, -297.5, and -387.5 relative to the transcription start site.
2In the intergenic regulatory region the fucPIK and fucAO operons, there exist other potential CRP-binding sites, which are located at positions -80.5, -289.5, -297.5, and -387.5 relative to the transcription start site.


Transcription unit       
Name: fucU
Gene(s): fucU   Genome Browser M3D Gene expression COLOMBOS
Evidence: [IEP] Inferred from expression pattern
Reference(s): [5] Li Z., et al., 2019
Promoter
Name: fucUp
+1: 2938837
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 51
Sequence: ggtatggcgtaggggaatttaacagcccggaagaagcccgcgcacagattcattatcagtAccgttatttctacccgcaaa
                                                   -10      +1                   
Evidence: [RE]
[TIM]
Reference(s): [5] Li Z., et al., 2019


Transcription unit       
Name: fucR
Gene(s): fucR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [6] Zaslaver A., et al., 2006
Promoter
Name: fucRp
+1: Unknown
Evidence: [IEP]
Reference(s): [6] Zaslaver A., et al., 2006


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: forward
Evidence: [ICA] Inferred by computational analysis
Reference(s): [7] Merino E, et al., 2005
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -9.3 2934062 2934106 caccttctagCTAATAAGTGTGACCGCCGTCATATTACAGAGCGTTTTTTATTTgaaaatgaat
  terminator -16.0 2937391 2937431 cccggtcgctCCGGCTACCGGGCCTGAACAAGCAAGAGTGGTTAGCCGGAtaagcaatgt
  terminator -14.1 2939324 2939342 ataccggtacGCCCGCATGACGCGGGCGgttatcgaat
  anti-terminator -10.9 2934037 2934080 taaagtgatgGTAGTCACATAAAGTCACCTTCTAGCTAATAAGTGTGACCGCCgtcatattac
  anti-anti-terminator -4.6 2934032 2934055 attattaaagTGATGGTAGTCACATAAAGTCACcttctagcta
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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