RegulonDB RegulonDB 10.7: Operon Form
   

folA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: folA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: folA
Gene(s): folA   Genome Browser M3D Gene expression COLOMBOS
Note(s): Both TyrR sites, together with the IHF site present in the folA upstream region, form a complex that is designed to respond primarily to the increased levels of tyrosine by activating the expression of folA |CITS:[17557822]|.
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Blanchin-Roland S., et al., 1986
Promoter
Name: folAp
+1: 49799
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 24
Sequence: ttcctcaacatcatcctcgcaccagtcgacgacggtttacgctttacgtatagtggcgacAattttttttatcgggaaatc
                         -35                     -10        +1                   
Evidence: [HIPP]
[RS-EPT-CBR]
Reference(s): [1] Blanchin-Roland S., et al., 1986
[2] Salgado H, et al., 2012
[3] Smith DR., et al., 1982
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal IHF activator folAp 49728 49740 -65.0 tcgccagcagAATATAAAATTTTcctcaacatc nd [APIORCISFBSCS], [GEA] [4]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote TyrR-tyrosine activator folAp 49642 49659 -148.5 taaagagtgaCGTAAATCACACTTTACAgctaactgtt nd [APIORCISFBSCS], [BPP], [GEA], [SM] [4]
remote TyrR-tyrosine activator folAp 49684 49701 -106.0 tttgtttcatTGTAATGCGGCGAGTCCAgggagagagc nd [APIORCISFBSCS], [BPP], [GEA], [SM] [4]





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