RegulonDB RegulonDB 10.8: Operon Form
   

manA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: manA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: manA
Gene(s): manA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [IHBCE] Inferred by a human based on computational evidence
[LTED] Length of transcript experimentally determined
Reference(s): [1] Miles JS., et al., 1984
[2] Miles JS., et al., 1984
Promoter
Name: manAp
+1: 1688551
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 25
Sequence: cgactttttgcggctccaggttacttcccgtaggattcttgctttaatagtgggattaatTtccacattaaaacagggatt
                               -35                    -10   +1                   
Evidence: [TIM]
Reference(s): [2] Miles JS., et al., 1984
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP activator manAp 1688476 1688499 -64.0 tttttaacaaAAACTGAGACTAGTACGACTTTTTgcggctccag nd [APIORCISFBSCS], [CV(GEA)], [GEA] [2], [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP repressor manAp 1688550 1688549 -1.5 nd nd [APIORCISFBSCS], [CV(GEA)], [GEA] [1], [3]
proximal CRP-cAMP repressor manAp 1688558 1688557 7.5 nd nd [APIORCISFBSCS], [CV(GEA)], [GEA] [1], [3]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: forward
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -10.4 1688529 1688566 gtaggattctTGCTTTAATAGTGGGATTAATTTCCACATTAAAACAGggattgatca
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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