RegulonDB RegulonDB 10.8: Operon Form
   

ung operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: ung
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: ung
Gene(s): ung   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Varshney U., et al., 1988
Promoter
Name: ungp
+1: 2716738
Distance from start of the gene: 16
Sequence: taaaaaatgagcatgattttgttctgtagaaagaagcagttaagctaggcggattgaagaTtcgcaggagagcgagatggc
Evidence: [CV(RS-EPT-CBR)]
[CV(TIM)]
[HIPP]
[RS-EPT-CBR]
[TIM]
Reference(s): [2] Salgado H, et al., 2012
[1] Varshney U., et al., 1988
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CpxR-Phosphorylated1 repressor ungp 2716650 2716664 -81.0 attttaccaaTTTACATTTTTTTGCactcgtttaa nd [BCE], [BPP] [3]
Note(s): 1ung transcription is negatively regulated by CpxR in the stationary phase. The affinity of CpxR to the CpxR box of the ung promoter region is increased by phosphorylation. This site was previously predicted by De Wulf P,2002
Near the ung promoter, in the CpxR box, there is an AT-rich sequence corresponding to the UP element. It is probable that CpxR binding to the ung promoter represses its transcription by interfering with the ability of the α-CTD to bind to the UP element.
1ung transcription is negatively regulated by CpxR in the stationary phase. The affinity of CpxR to the CpxR box of the ung promoter region is increased by phosphorylation. This site was previously predicted by De Wulf P,2002
Near the ung promoter, in the CpxR box, there is an AT-rich sequence corresponding to the UP element. It is probable that CpxR binding to the ung promoter represses its transcription by interfering with the ability of the α-CTD to bind to the UP element.





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