RegulonDB RegulonDB 10.6.3: Operon Form
   

cspI operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: cspI
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Gene(s): cspI   Genome Browser M3D Gene expression COLOMBOS
Note(s): Expression levels of cspI, ypjB, and yhjX genes were repressed by overproduction of YehT |CITS:[22685278]|. Insomuch as all of these genes lack any LytTR-like sequence motif, it is probable that the effect of YehT on these genes is indirect |CITS:[22685278]|.
In spite of showing a match to the consensus CRP, cspB, cspG, and cspI are regulated indirectly by CRP-cAMP during growth at 37oC as well as 15oC |CITS:[25637299]|. It is probable that putative sites in these genes have become degenerate and have lost the binding function during the evolutionary process |CITS:[25637299]|.
Promoter
Name: cspIp2
+1: 1638712
Distance from start of the gene: 45
Sequence: attttattatttgtacctcttgagatttccttgttggtttttctctctgatattttttttCggaccattctgcccaagggc
Note(s): The transcription start site for cspIp2 was determined by 5-RACE; however, the experimental data were not provided in the report Kraxenberger T,2012
Evidence: [TIM]
Reference(s): [1] Kraxenberger T., et al., 2012


Transcription unit          
Name: cspI
Gene(s): cspI   Genome Browser M3D Gene expression COLOMBOS
Note(s): The cspI gene was significantly upregulated in bacterial cells associated with lettuce roots in a microarray analysis |CITS: [22830299]|.
In spite of showing a match to the consensus CRP, cspB, cspG, and cspI are regulated indirectly by CRP-cAMP during growth at 37oC as well as 15oC |CITS:[25637299]|. It is probable that putative sites in these genes have become degenerate and have lost the binding function during the evolutionary process |CITS:[25637299]|.
Promoter
Name: cspIp
+1: 1638812
Distance from start of the gene: 145
Sequence: gtgtttttctttacaaaagtaatccttgctatgggtggttaatcatgcgttaatggtgttCtggtttgttacaaatttatc
Evidence: [TIM]
Reference(s): [2] Wang N., et al., 1999
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote BasR-Phosphorylated activator cspIp 1638940 1638959 -137.5 tccatgagccAAAATTCCTGAAATCTTAAGggtaagataa nd [BPP], [HIBSCS] [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote Fis repressor cspIp 1638757 1638771 49.0 attgttataaTTTTATTATTTGTACctcttgagat nd [AIBSCS], [GEA] [4]
remote Fis repressor cspIp 1638765 1638779 41.0 aagcagtcatTGTTATAATTTTATTatttgtacct nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638792 1638806 14.0 tgttctggttTGTTACAAATTTATCtgaagcagtc nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638825 1638839 -20.0 ccttgctatgGGTGGTTAATCATGCgttaatggtg nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638888 1638902 -83.0 gacacgttttATTAATAAATAAAGCtattctttca nd [AIBSCS], [GEA] [4]
proximal Fis repressor cspIp 1638893 1638907 -88.0 agaatgacacGTTTTATTAATAAATaaagctattc nd [AIBSCS], [GEA] [4]





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