RegulonDB RegulonDB 10.8: Operon Form
   

yeaGH operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: yeaGH
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: yeaGH
Gene(s): yeaG, yeaH   Genome Browser M3D Gene expression COLOMBOS
Note(s): The yeaGH operon is highly expressed during the initial adaptive response to nitrogen starvation. It is also highly expressed in response to diverse stresses, including low pH Weber H,2005 hyperosmotic conditions 11742689 entry into stationary phase Weber H,2005 nitrogen starvation Brown DR,2014 sulfur limitation 15659685 growth in biofilms 12657059 and exposure to the antimicrobial peptide polymyxin B 17010160 It is conserved across several bacterial species, especially among Enterobacteriaceae, including species pathogenic to plants or animals Brown DR,2014. Figueira R,2015. Zimmer DP,2000 and alongside relA it constitutes a new branch in the Ntr response 30514772
Evidence: [IC] Inferred by curator
Promoter
Name: yeaGp2
+1: 1866765
Distance from start of the gene: 143
Sequence: ccgtgcaggcaagttttccatttgccatctacgcttaattttgaaggtgtatcaccgggcAcgttgttctcatcgtcgata
Evidence: [HTIM]
Reference(s): [1] Mendoza-Vargas A., et al., 2009


Transcription unit          
Name: yeaGH
Gene(s): yeaG, yeaH   Genome Browser M3D Gene expression COLOMBOS
Note(s): The yeaGH operon is highly expressed during the initial adaptive response to nitrogen starvation. It is also highly expressed in response to diverse stresses, including low pH Weber H,2005 hyperosmotic conditions 11742689 entry into stationary phase Weber H,2005 nitrogen starvation Brown DR,2014 sulfur limitation 15659685 growth in biofilms 12657059 and exposure to the antimicrobial peptide polymyxin B 17010160 It is conserved across several bacterial species, especially among Enterobacteriaceae, including species pathogenic to plants or animals Brown DR,2014. Figueira R,2015. Zimmer DP,2000 and alongside relA it constitutes a new branch in the Ntr response 30514772
Reference(s): [2] Zimmer DP., et al., 2000
Promoter
Name: yeaGp1
+1: 1866815
Sigma Factor: Sigma54 Sigmulon
Distance from start of the gene: 93
Sequence: atcaccgggcacgttgttctcatcgtcgataaaatggcatgagagttgctgtgttttagcAagagacgtcgttcagtttac
                                   -24         -12          +1                   
Note(s): We assigned a putative transcription start site to this promoter based on the observation that the majority of the σ54-dependent promoters, whose transcription start sites were determined experimentally, present a distance of 11 nucleotides between the transcription start site and the -12 box Barrios H,1999.
Evidence: [AIPP]
Reference(s): [3] Reitzer L., et al., 2001
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd NtrC-Pasp activator yeaGp1 nd nd nd nd nd [GEA] [2]





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