RegulonDB RegulonDB 11.1: Operon Form
   

gudPXD operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: gudPXD
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: gudPXD
Gene(s): gudD, gudX, gudP   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for gudP . This structure could regulate the expression of the gene, as observed for hemL gene expression Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X,2020.
Evidence: [EXP-IDA-BOUNDARIES-DEFINED] Boundaries of transcription experimentally identified
Reference(s): [1] Monterrubio R., et al., 2000
Promoter
Name: gudPp
+1: Unknown
Evidence: [IC]
Reference(s): [1] Monterrubio R., et al., 2000
TF binding sites (TFBSs)
[CdaR,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd CdaR activator gudPp nd nd nd nd nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS] W [1], [2]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -6.5 2922246 2922268 ttgcacggtgAGCCGCTATGGCGCGCTTTTTAtactgctatt
  anti-terminator -12.3 2922265 2922308 gccaaaatcgGGCCTCATTGAACGCATTAATGTTGTGTTGTTGCACGGTGAGCcgctatggcg
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"


Evidence    

 [IC] Inferred by curator

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis


Reference(s)    

 [1] Monterrubio R., Baldoma L., Obradors N., Aguilar J., Badia J., 2000, A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli., J Bacteriol 182(9):2672-4

 [2] Sampaio MM., Chevance F., Dippel R., Eppler T., Schlegel A., Boos W., Lu YJ., Rock CO., 2004, Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor., J Biol Chem 279(7):5537-48

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