RegulonDB RegulonDB 10.6.3: Operon Form
   

zntA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: zntA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: zntA
Gene(s): zntA   Genome Browser M3D Gene expression COLOMBOS
Note(s): Zinc induced activation of zntA transcription in a microarray analysis |CITS:[16159766]|.
Promoter
Name: zntAp
+1: 3606422
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 29
Sequence: ctcgctgtatctctgataaaacttgactctggagtcgactccagagtgtatccttcggttAatgagaaaaaacttaaccgg
                       -35                       -10        +1                   
Evidence: [HIPP]
[RS-EPT-CBR]
[TIM] ; Method: Primer Extension
[TIM]
Reference(s): [1] Brocklehurst KR., et al., 1999
[2] Outten CE., et al., 1999
[3] Salgado H, et al., 2012
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal ZntR-Zn2+1 activator zntAp 3606387 3606408 -24.5 ataaaacttgACTCTGGAGTCGACTCCAGAGTgtatccttcg nd [BPP], [SM] [1], [2]
Note(s): 1zntA expression is controlled by the ZntR transcriptional activator in the presence of nanomolar levels of intracellular zinc in vivoWang D, Hosteen O, Fierke CA,20121zntA expression is controlled by the ZntR transcriptional activator in the presence of nanomolar levels of intracellular zinc in vivoWang D, Hosteen O, Fierke CA,2012


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: forward
Evidence: [ICA] Inferred by computational analysis
Reference(s): [4] null null
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -19.9 3606409 3606449 ctccagagtgTATCCTTCGGTTAATGAGAAAAAACTTAACCGGAGGATGCcatgtcgact
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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