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Name: | csrB |
Gene(s): | csrB Genome Browser M3D Gene expression COLOMBOS |
Note(s): | Based on gene expression analysis, Jonas K,2006determined that the csrB and csrC genes are under positive control of YhdA. However, they did not show direct evidence for YhdA binding to the crsBp and csrCp promoters. Although there are two potential binding sites for CRP, CRP1 (ttgTGAGAgatctcTTACAgac) and CRP2 (ctcGGTGTgtaatcTCTCCggt), on the regulatory regions of the csrB gene, it was found that CRP binds nonspecifically on these sites, negatively affecting csrB transcription in an indirect way Pannuri A,2016 Based on microarray and RT-qPCR analyses, it was determined that the csrB gene is downregulated upon exposure to glutathione (GSH) Goswami M,2018 |
Evidence: | [BTEI] Boundaries of transcription experimentally identified [LTED] Length of transcript experimentally determined |
Reference(s): | [1] Liu MY., et al., 1997 |
Promoter | |
Name: | csrBp |
+1: | 2924524 |
Sigma Factor: | Sigma70 Sigmulon |
Distance from start of the gene: | 0 |
Sequence: |
ccttaaggcattgtctgtaagcgccttgtaagacttcgcgaaaaagacgattctatcttcGtcgacagggagtcagacaac -35 -10 +1 |
Evidence: |
[CV(RS-EPT-CBR/TA)] [CV(TA/TIM)] [HTIM] [RS-EPT-CBR] [TIM] |
Reference(s): |
[2] Gudapaty S., et al., 2001 [3] Mendoza-Vargas A., et al., 2009 [4] Salgado H, et al., 2012 |
Terminator(s) | |
Type: | rho-independent |
Sequence: | aataaaaaaaGGGAGCACTGTATTCACAGCGCTCCCggttcgtttc |
Reference(s): | [1] Liu MY., et al., 1997 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | IHF | activator | csrBp | 2924617 | 2924629 | -99.0 | tttcatttaaAATCAAAATGTTGattgttaatt | nd | [AIBSCS], [CV(GEA/ROMA)], [GEA] | [5] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | UvrY-Phosphorylated | activator | csrBp | 2924698 | 2924716 | -183.0 | ccccatctggTTGTGAGAGATCTCTTACAgactctgtag | nd | [BPP], [GEA] | [5] |
Reference(s) |
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