RegulonDB RegulonDB 10.8: Operon Form
   

gnd operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: gnd
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: gnd
Gene(s): gnd   Genome Browser M3D Gene expression COLOMBOS
Note(s): Under nitrogen-rich growth conditions, the expression of the gnd gene was increased in mutants for two genes that encode two terminal oxidases, cyoA and cydB, and in mutants for two transcriptional regulators, Fnr and Fur. However, it is unknown if the effects of the transcriptional regulators act directly on gene expressionKumar R,2011
The expression of the gene gnd is increased under acidic growth conditions in microaerobiosis Marzan LW,2013
A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for gnd . This structure could regulate the expression of the gene, as observed for hemL gene expression 31964733.
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Nasoff MS., et al., 1984
Promoter
Name: gndp
+1: 2101324
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 56
Sequence: aagcatataagcatggataagctatttatactttaataagtactttgtatacttatttgcGaacattccaggccgcgagca
                         -35                    -10         +1                   
Evidence: [CV(RS-EPT-CBR)]
[CV(TIM)]
[RS-EPT-CBR]
[TIM]
Reference(s): [2] Baker HV., et al., 1984
[1] Nasoff MS., et al., 1984
[3] Salgado H, et al., 2012
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd FNR repressor gndp nd nd nd nd nd [GEA] [5]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd Fur-Fe2+ repressor gndp nd nd nd nd nd [GEA] [5]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd GadE activator gndp nd nd nd nd nd [GEA] [4]





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