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Name: | acrD | |||||||||
Gene(s): | acrD Genome Browser M3D Gene expression COLOMBOS | |||||||||
Note(s): | During an experiment using increasing concentrations of tetracycline, the transcription of the acrD gene was induced in low concentrations (1.5 and 4 mg/L), but this induction decreased in high concentrations (10 mg/L) Viveiros M, Dupont M, Rodrigues L, Couto I, Davin-Regli A, Martins M, Pagès JM, Amaral L,2007 acrD expression is increased at least 5-fold by indole Hirakawa H,2005. | |||||||||
Promoter | ||||||||||
Name: | acrDp | |||||||||
+1: | 2587475 | |||||||||
Sigma Factor: | Sigma70 Sigmulon | |||||||||
Distance from start of the gene: | 120 | |||||||||
Sequence: |
aaagtcagttaatgtaatgcctcctactgaccaaagaatacttgcacttaaggttcagtaTaaaagggcatgataatttac -35 -10 +1 |
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Evidence: |
[AIPP] [ICWHO] |
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Reference(s): | [1] Huerta AM., et al., 2003 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
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LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | EvgA-phosphorylated | activator | acrDp | 2587435 | 2587453 | -31.5 | aatgtaatgcCTCCTACTGACCAAAGAATacttgcactt | nd | [GEA], [AIBSCS] | [2] |
Name: | acrD | |||||||||
Gene(s): | acrD Genome Browser M3D Gene expression COLOMBOS | |||||||||
Note(s): | During an experiment using increasing concentrations of tetracycline, the transcription of the acrD gene was induced in low concentrations (1.5 and 4 mg/L), but this induction decreased in high concentrations (10 mg/L) Viveiros M, Dupont M, Rodrigues L, Couto I, Davin-Regli A, Martins M, Pagès JM, Amaral L,2007 acrD expression is increased at least 5-fold by indole Hirakawa H,2005. | |||||||||
Promoter | ||||||||||
Name: | acrDp2 | |||||||||
+1: | 2587550 | |||||||||
Sigma Factor: | Sigma54 Sigmulon | |||||||||
Distance from start of the gene: | 45 | |||||||||
Sequence: |
atttacattaactcctttttttctccacgattggctcgtaccttgccgctacagtgaagcAagtcaagcctacaacgatac -24 -12 +1 |
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Note(s): | This promoter was identified by microarray assays with a mutant σ54 strain and a σ54-overexpressing strain, and by σ54-related promoter element identification Zhao K,2010 We assigned a putative transcription start site to this promoter based on the observation that the majority of the σ54-dependent promoters, whose transcription start sites were determined experimentally, present a distance of 11 nucleotides between the transcription start site and the -12 box Barrios H,1999. |
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Evidence: |
[HIPP] [ICWHO] [IEP] [IHBCE] |
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Reference(s): |
[1] Huerta AM., et al., 2003 [3] Zhao K., et al., 2010 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | BaeR-phosphorylated | activator | acrDp2 | 2587504 | 2587523 | -36.5 | acattaactcCTTTTTTTCTCCACGATTGGctcgtacctt | nd | [GEA], [IC], [BPP], [IC] | [4] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | CpxR-phosphorylated | activator | acrDp2 | 2587414 | 2587432 | -127.5 | ggagggtgagGAAAGTCAGTTAATGTAATgcctcctact | nd | [GEA], [IC], [BPP], [IC] | [4] |
remote | CpxR-phosphorylated | activator | acrDp2 | 2587446 | 2587459 | -98.0 | tcctactgacCAAAGAATACTTGCacttaaggtt | nd | [IC], [BPP], [IC] | [4] |
proximal | CpxR-phosphorylated | activator | acrDp2 | 2587476 | 2587493 | -66.0 | ggttcagtatAAAAGGGCATGATAATTTacattaactc | nd | [GEA], [IC], [BPP], [IC] | [4] |
Reference(s) |
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