RegulonDB RegulonDB 10.6.3: Operon Form
   

mntH operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: mntH
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: mntH
Gene(s): mntH   Genome Browser M3D Gene expression COLOMBOS
Note(s): MntS makes manganese more available in cells, promoting the ability of manganese to repress mntH transcription by altering cellular manganese pools and global availability, which would perturb MntR and/or Fur activity |CITS:[21908668]|.
Evidence: [AISGDTU] Automated inference that a single-gene directon is a transcription unit
Promoter
Name: mntHp
+1: 2512734
Sigma Factor: Sigma70, Sigma70
Distance from start of the gene: 28
Sequence: tcaccacaatccatttaaatgaatttgataatcattctcgtttggcatagcatgaaacatAgcaaaggctatgttttagag
                         -10                    -35         +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [1] Kehres DG., et al., 2002
[2] Waters LS., et al., 2011
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fur-Fe2+1 repressor mntHp 2512757 2512775 -31.5 tccatttaaaTGAATTTGATAATCATTCTcgtttggcat nd [AIBSCS], [HIBSCS], [IGI] [1], [5]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal MntR-Mn2+ repressor mntHp 2512719 2512740 5.5 gcatagcatgAAACATAGCAAAGGCTATGTTTtagaggcaca nd [AIBSCS], [BPP], [GEA] [1], [5]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal OxyR activator mntHp 2512780 2512796 -54.0 ctatcagagaAATCACCACAATCCATTtaaatgaatt nd [AIBSCS], [GEA], [SM] [1], [3]
proximal OxyR activator mntHp 2512802 2512818 -76.0 ttttcgtagtCATAATCCTGGTCTATCagagaaatca nd , [GEA], [HIBSCS], [IHBCE], , [SM] [1], [3], [4]
Note(s): 1Iron represses mntH expression. This repression is mediated by Fur, a transcriptional regulator that binds 59 nt upstream of the mntH gene start Patzer SI,2001.3Iron represses mntH expression. This repression is mediated by Fur, a transcriptional regulator that binds 59 nt upstream of the mntH gene start Patzer SI,2001.


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: reverse
Evidence: [ICA] Inferred by computational analysis
Reference(s): [6] null null
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -15.1 2512708 2512753 tcattctcgtTTGGCATAGCATGAAACATAGCAAAGGCTATGTTTTAGAGGCACAagatgacgaa
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





RegulonDB