RegulonDB RegulonDB 10.6.3: Operon Form
   

evgAS operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: evgAS
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: evgAS
Gene(s): evgA, evgS   Genome Browser M3D Gene expression COLOMBOS
Note(s): The evgAS operon was inferred based on the facts that evgA and evgS are adjacent genes, encoded in the same direction, and their products are part of the two-component system EvgS/EvgA. EvgS is the sensor protein and EvgA is theresponse regulator |CITS: [8125343]|.
The expression of the gene evgA is increased under acidic growth conditions in either aerobiosis or microaerobiosis |CITS:[23274360]|. The increased expression under aerobiosis appears to be caused by the transcription factor PhoB |CITS:[23274360]|, but it is not known which promoter, of two transcribing evgA, is affected by PhoB.
Evidence: [IC] Inferred by curator
Promoter
Name: evgAp2
+1: 2483631
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 124
Sequence: atcggtacaatccctgattttattgttgacatttcatttatgccgactatttatatggtaTacttgtcgaattatcttaaa
                                 -35                  -10   +1                   
Evidence: [TIM]
Reference(s): [1] Tanabe H., et al., 1998
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote EvgA-Phosphorylated activator evgAp2 2483513 2483530 -109.5 tgcaatacaaTTCTTACGCCTGTAGGATtagtaagaag nd [AIBSCS], [BPP], [GEA], [HIBSCS] [1], [2], [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd H-NS repressor evgAp2 nd nd nd nd nd [BPP] [4]


Transcription unit          
Name: evgAS
Gene(s): evgA, evgS   Genome Browser M3D Gene expression COLOMBOS
Note(s): The evgAS operon was inferred based on the facts that evgA and evgS are adjacent genes, encoded in the same direction, and their products are part of the two-component system EvgS/EvgA. EvgS is the sensor protein and EvgA is theresponse regulator |CITS: [8125343]|.
The expression of the gene evgA is increased under acidic growth conditions in either aerobiosis or microaerobiosis |CITS:[23274360]|. The increased expression under aerobiosis appears to be caused by the transcription factor PhoB |CITS:[23274360]|, but it is not known which promoter, of two transcribing evgA, is affected by PhoB.
Evidence: [IC] Inferred by curator
Promoter
Name: evgAp1
+1: 2483641
Sigma Factor: Sigma38 Sigmulon
Distance from start of the gene: 114
Sequence: tccctgattttattgttgacatttcatttatgccgactatttatatggtatacttgtcgaAttatcttaaaggaagctcag
                           -35              -10             +1                   
Evidence: [RS-EPT-CBR]
[TIM]
Reference(s): [5] Salgado H, et al., 2012
[1] Tanabe H., et al., 1998
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote EvgA-Phosphorylated activator evgAp1 2483513 2483530 -119.5 tgcaatacaaTTCTTACGCCTGTAGGATtagtaagaag nd [AIBSCS], [BPP], [GEA], [HIBSCS] [1], [2], [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd H-NS repressor evgAp1 nd nd nd nd nd [BPP] [4]





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