RegulonDB RegulonDB 10.7: Operon Form
   

recN operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: recN
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: recN
Gene(s): recN   Genome Browser M3D Gene expression COLOMBOS
Note(s): The recN gene is repressed by both DnaA and LexA in an independent manner, but the two proteins act in an additive manner during the SOS response |CITS:[29967594]|.
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: recNp
+1: 2751759
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 36
Sequence: aattattctaattttacgccagcctctttactgtatataaaaccagtttatactgtacacAataacagtaatggtttttca
                           -35                   -10        +1                   
Note(s): We assigned a putative transcription start site to this promoter based on the observation that the majority of the promoters, whose transcription start sites were determined experimentally, present a distance of 6 nucleotides between the transcription start site and the -10 box.
Evidence: [HIPP]
Reference(s): [1] Rostas K., et al., 1987
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal DnaA-ATP repressor recNp 2751730 2751738 -25.0 gcctctttacTGTATATAAaaccagttta nd [GEA], [ICA] [2]
proximal DnaA-ATP repressor recNp 2751751 2751759 -4.0 ccagtttataCTGTACACAataacagtaa nd [GEA], [ICA] [2]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal LexA1 repressor recNp 2751727 2751746 -22.5 ccagcctcttTACTGTATATAAAACCAGTTtatactgtac nd [AIBSCS], [BPP], [GEA] [1], [2]
proximal LexA2 repressor recNp 2751749 2751768 -0.5 aaccagtttaTACTGTACACAATAACAGTAatggtttttc nd [AIBSCS], [BPP], [GEA] [1], [2]
Note(s): 1The promoter region of the recN gene contains two 16-bp sequences, separated by 6 bp, that match the consensus sequence (SOS box) for binding LexA protein Rostas K,1987
2The promoter region of the recN gene contains two 16-bp sequences, separated by 6 bp, that match the consensus sequence (SOS box) for binding LexA protein Rostas K,19872The promoter region of the recN gene contains two 16-bp sequences, separated by 6 bp, that match the consensus sequence (SOS box) for binding LexA protein Rostas K,1987
4The promoter region of the recN gene contains two 16-bp sequences, separated by 6 bp, that match the consensus sequence (SOS box) for binding LexA protein Rostas K,1987





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