RegulonDB RegulonDB 10.10: Operon Form
   

bacA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: bacA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: bacA
Synonym(s): uppP
Gene(s): bacA   Genome Browser M3D Gene expression COLOMBOS
Reference(s): [1] Rhodius VA., et al., 2005
Promoter
Name: bacAp
+1: 3204175
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 44
Sequence: aaagaaaataattaattttacagctgttaaaccaaacggttataacctggtcatacgcagTagttcggacaagcggtacat
                             -35                   -10      +1                   
Note(s): The transcriptional start site of the uppPp promoter was also determined by Rhodius VA,2005, and it was different by 1 bp from the one characterized by Rezuchova B,2003.
Evidence: [AIBSCS]
[AIPP]
[ICWHO]
[TIM]
Reference(s): [2] Huerta AM., et al., 2003
[3] Rezuchova B., et al., 2003
TF binding sites (TFBSs)
[CpxR,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CpxR-phosphorylated activator bacAp 3204460 3204474 -292.0 tgggataaccGTAAAGCGGCGAAAAgtgatgatgt nd [ICA] [4]


Evidence    

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [AIPP] Automated inference of promoter position

 [ICWHO] Inferred computationally without human oversight

 [TIM] Transcription initiation mapping

 [ICA] Inferred by computational analysis


Reference(s)    

 [1] Rhodius VA., Suh WC., Nonaka G., West J., Gross CA., 2005, Conserved and variable functions of the sigmaE stress response in related genomes., PLoS Biol 4(1):e2

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Rezuchova B., Miticka H., Homerova D., Roberts M., Kormanec J., 2003, New members of the Escherichia coli sigmaE regulon identified by a two-plasmid system., FEMS Microbiol Lett 225(1):1-7

 [4] De Wulf P., McGuire AM., Liu X., Lin EC., 2002, Genome-wide profiling of promoter recognition by the two-component response regulator CpxR-P in Escherichia coli., J Biol Chem 277(29):26652-61

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