![]() ![]() ![]() ![]() |
Name: | spy | |||||||||
Gene(s): | spy Genome Browser M3D Gene expression COLOMBOS | |||||||||
Note(s): | spy gene expression is induced separately by both copper and zinc metals through the CpxAR and BaeSR sensor response regulatory systems, respectively. BaeR can be the primary regulator and CpxR can enhance its function Yamamoto K,2008. Srivastava SK, Lambadi PR, Ghosh T, Pathania R, Navani NK,2014 On the other hand, BaeR is the primary regulator of spy in the presence of the protein-unfolding agent ethanol Srivastava SK, Lambadi PR, Ghosh T, Pathania R, Navani NK,2014 The expression of the gene spy is increased when colicin (at 30 ng/ml) is added to the medium Kamen?ek S, ?gur-Bertok D,2013. spy is also induced by indole Hirakawa H,2005. Raffa RG,2002. Under conditions leading to NlpE outer membrane lipoprotein overexpression, the transcription of the spy gene is increased by CpxR Raivio TL,2013 The spy gene is upregulated by long-term (8 to 12 h) exposure of E. coli to some biocides Merchel Piovesan Pereira B, Wang X, Tagkopoulos I,2020. |
|||||||||
Evidence: | [BTEI] Boundaries of transcription experimentally identified [LTED] Length of transcript experimentally determined |
|||||||||
Reference(s): |
[1] Hagenmaier S., et al., 1997 [2] Nishino K., et al., 2005 |
|||||||||
Promoter | ||||||||||
Name: | spyp | |||||||||
+1: | 1825688 | |||||||||
Sigma Factor: | Sigma70 Sigmulon | |||||||||
Distance from start of the gene: | 63 | |||||||||
Sequence: |
acactttcattgttttaccgttgctctgattaattgacgctaaagtcagtaaagttaatcTcgtcaacacggcacgctact -35 -10 +1 |
|||||||||
Evidence: |
[HIPP] [ICWHO] [TIM] |
|||||||||
Reference(s): |
[1] Hagenmaier S., et al., 1997 [3] Huerta AM., et al., 2003 [4] Yamamoto K., et al., 2006 |
|||||||||
Terminator(s) | ||||||||||
Type: | rho-independent | |||||||||
Sequence: | ttgagaagagAAAAGAAAACCGCCGATCCTGTCCACCGCATTACTGCAAGGTAGTGGACAAGACCGGCGGTCTTAAGTTTtttggctgaa | |||||||||
Reference(s): | [1] Hagenmaier S., et al., 1997 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | BaeR-phosphorylated | activator | spyp | 1825765 | 1825784 | -86.5 | atcaaattttCTTTTTTTCTCCATAATTGGcgcaaaagtg | nd | [GEA], [AIBSCS], [APIORCISFBSCS], [BPP] | [2], [5], [6] |
remote | BaeR-phosphorylated | activator | spyp | 1825836 | 1825855 | -157.5 | ccagtcatccGGTATAGTTCTTCATAATCTctgcaaaatc | nd | [IC], [APIORCISFBSCS], [BPP], [IC] | [5] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
proximal | CpxR-phosphorylated | activator | spyp | 1825731 | 1825745 | -50.0 | gttttttacaCTTTCATTGTTTTACcgttgctctg | nd | [GEA], [APIORCISFBSCS], [BPP] | [4], [6], [7], [8] |
Reference(s) |
![]() |
---|---|