RegulonDB RegulonDB 10.8: Operon Form
   

flhBAE operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: flhBAE
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: flhBAE
Gene(s): flhE, flhA, flhB   Genome Browser M3D Gene expression COLOMBOS
Note(s): There is a consensus sequence for a σ28 factor at 120 bp upstream of the transcription initiation site of the flhBp promoter, which could be a second promoter for the flhB operon Liu X,1994 The DNA sequence was not shown.
In a study where it was shown that the L-tryptophan eradicated persister cells, it was observed that the exogenous amino acid downregulated the expression of flhB as well as other flagellar genes 31271063.
Evidence: [ITC] Inferred through co-regulation
Promoter
Name: flhBp
+1: 1966216
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 25
Sequence: cgcctgttttgccccttactcaaaccattgaacgctttgcgctctggcatcattcacgctTaatactctttccaggattgg
Evidence: [HIPP]
[TAS]
Reference(s): [1] Liu X., et al., 1994
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal FlhDC activator flhBp 1966247 1966263 -39.0 ctgttttgccCCTTACTCAAACCATTGaacgctttgc nd [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1], [2]
proximal FlhDC activator flhBp 1966275 1966293 -67.5 atgtgtggcaGCAAAAGCCCTAAATCCCGcctgttttgc nd [APIORCISFBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1], [2]





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