RegulonDB RegulonDB 11.0: Operon Form
   

pgaABCD operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: pgaABCD
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: pgaABCD
Gene(s): pgaD, pgaC, pgaB, pgaA   Genome Browser M3D Gene expression COLOMBOS
Note(s): The pgABCD operon was inferred based on the facts that its genes are adjacent, encoded in the same direction, and their products are all involved in biofilm formation Wang X, Preston JF, Romeo T,2004
H-NS represses pgaA transcription, although it is unknown if the effect is direct or indirect Parker A,2017
The Rho protein appears to negatively regulate expression of the operon pgaABCD during the log phase of growth Hafeezunnisa M, Sen R,2020.
Evidence: [IC] Inferred by curator
Promoter
Name: pgaAp
+1: 1092523
Distance from start of the gene: 234
Sequence: ccgaaatcatgcatcggaatttactgatttaattattttaatcctaatttattttgaaaaAggcattgggatttatgccgt
Evidence: [TIM]
Reference(s): [1] Goller C., et al., 2006
[2] Wang X., et al., 2005
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal NhaR-Na+ activator pgaAp 1092556 1092572 -41.0 cgaaatcatgCATCGGAATTTACTGATttaattattt nd [GEA], [APIORCISFBSCS], [BPP] [1], [3]
proximal NhaR-Na+ activator pgaAp 1092578 1092594 -63.0 tcatcaggacTTTCGAAAAATCCGAAAtcatgcatcg nd [GEA], [APIORCISFBSCS], [BPP] [1], [3]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal OmpR-phosphorylated repressor pgaAp 1092545 1092564 -31.5 tgcatcggaaTTTACTGATTTAATTATTTTaatcctaatt nd [GEA], [APIORCISFBSCS], [BPP] [4]





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