RegulonDB RegulonDB 10.8: Operon Form
   

can operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: can
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: can
Gene(s): can   Genome Browser M3D Gene expression COLOMBOS
Evidence: [AISDTU] Automated inference that a single-gene directon is a transcription unit
[IEP] Inferred from expression pattern
Reference(s): [1] Nonaka G., et al., 2006
Promoter
Name: canp
+1: 142703
Sigma Factor: Sigma32, Sigma70
Distance from start of the gene: 33
Sequence: ttacgttcttacactttatctgtggtttaaatcgtcccggagttgccctatattagccaaAcgtaattatttggttacagg
Evidence: [AIPP]
[CV(RS-EPT-CBR)]
[HTIM]
[IDA]
[RS-EPT-CBR]
Reference(s): [2] Mendoza-Vargas A., et al., 2009
[1] Nonaka G., et al., 2006
[3] Salgado H, et al., 2012


Evidence    

 [AIPP] Automated inference of promoter position

 [CV(RS-EPT-CBR)] cross validation(RS-EPT-CBR)

 [HTIM] High-throughput transcription initiation mapping

 [IDA] Inferred from direct assay

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Nonaka G., Blankschien M., Herman C., Gross CA., Rhodius VA., 2006, Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress., Genes Dev 20(13):1776-89

 [2] Mendoza-Vargas A., Olvera L., Olvera M., Grande R., Vega-Alvarado L., Taboada B., Jimenez-Jacinto V., Salgado H., Juarez K., Contreras-Moreira B., Huerta AM., Collado-Vides J., Morett E., 2009, Genome-wide identification of transcription start sites, promoters and transcription factor binding sites in E. coli., PLoS One 4(10):e7526

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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