RegulonDB RegulonDB 10.8: Operon Form
   

allA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: allA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: allA
Gene(s): allA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Cusa E., et al., 1999
Promoter
Name: allAp
+1: 532390
Distance from start of the gene: 61
Sequence: tggaaaaatattccaacttttgtattgatgttgttctcttaaggttttagattgcctgttAttgaaaccaagctgaccggt
Evidence: [TIM]
Reference(s): [2] Rintoul MR., et al., 2002
TF binding sites (TFBSs)
[AllR,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal AllR-allantoin repressor allAp 532329 532345 -53.0 aaatctagttTTGGAAAAATATTCCAActtttgtatt nd [BCE], [BPP], [CV(GEA)], [CV(GEA)], [CV(GEA/SM)], [CV(SM)], [GEA], [SM] [2], [3]


Evidence    

 [TIM] Transcription initiation mapping

 [BCE] Binding of cellular extracts

 [BPP] Binding of purified proteins

 [CV(GEA)] cross validation(GEA)

 [CV(GEA/SM)] cross validation(GEA/SM)

 [CV(SM)] cross validation(SM)

 [GEA] Gene expression analysis

 [SM] Site mutation


Reference(s)    

 [1] Cusa E., Obradors N., Baldoma L., Badia J., Aguilar J., 1999, Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli., J Bacteriol 181(24):7479-84

 [2] Rintoul MR., Cusa E., Baldoma L., Badia J., Reitzer L., Aguilar J., 2002, Regulation of the Escherichia coli allantoin regulon: coordinated function of the repressor AllR and the activator AllS., J Mol Biol 324(4):599-610

 [3] Hasegawa A., Ogasawara H., Kori A., Teramoto J., Ishihama A., 2008, The transcription regulator AllR senses both allantoin and glyoxylate and controls a set of genes for degradation and reutilization of purines., Microbiology 154(Pt 11):3366-78

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