RegulonDB RegulonDB 10.7: Operon Form
   

slt operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: slt
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Gene(s): slt   Genome Browser M3D Gene expression COLOMBOS
Note(s): Under NlpE outer membrane lipoprotein overexpression, the transcription of the slt gene is increased by CpxR |CITS:[ 23564175]|.
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: sltp7
+1: 4630700
Sigma Factor: Sigma32 Sigmulon
Distance from start of the gene: 33
Sequence: cgtaacgtggcgtaaacggcaatgactggttagcataaatctattacgcggcatgacgctGcattgatgtatttacactta
                          -35                    -10        +1                   
Note(s): Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 4.529. P-value: 5.119e-5
Evidence: [ICWHO]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CpxR-Phosphorylated1 activator sltp7 4630641 4630656 -52.0 aaaagtgtccGTAACGTGGCGTAAACggcaatgact nd [AIBSCS], [APIORCISFBSCS], [BPP], [GEA], [IGI] [2], [3]
Note(s): 1The regulation of CpxR on the slt gene has been probed by quantitative PCR analysis of cDNA and by the identification of a consensus DNA-binding site of CpxR in the regulatory region of slt Raivio TL,2013 The identification of this DNA-binding site was only mentioned in the paper of Raivio et al. (2013), but the DNA sequence was not shown Raivio TL,20131The regulation of CpxR on the slt gene has been probed by quantitative PCR analysis of cDNA and by the identification of a consensus DNA-binding site of CpxR in the regulatory region of slt Raivio TL,2013 The identification of this DNA-binding site was only mentioned in the paper of Raivio et al. (2013), but the DNA sequence was not shown Raivio TL,2013





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