RegulonDB RegulonDB 11.2: Operon Form
   

slt operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: slt
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: slt
Gene(s): slt   Genome Browser M3D Gene expression COLOMBOS
Note(s): Under NlpE outer membrane lipoprotein overexpression, the transcription of the slt gene is increased by CpxR Raivio TL,2013
Evidence: [COMP-AINF] Inferred computationally without human oversight
Promoter
Name: sltp7
+1: 4630700
Sigma Factor: Sigma32 Sigmulon
Distance from start of the gene: 33
Sequence: cgtaacgtggcgtaaacggcaatgactggttagcataaatctattacgcggcatgacgctGcattgatgtatttacactta
                          -35                    -10        +1                   
Evidence: [COMP-AINF]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
[CpxR,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence Confidence level (C: Confirmed, S: Strong, W: Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CpxR-phosphorylated activator sltp7 4630641 4630656 -52.0 aaaagtgtccGTAACGTGGCGTAAACggcaatgact nd [EXP-IEP-GENE-EXPRESSION-ANALYSIS], [EXP-IGI], [COMP-AINF-SIMILAR-TO-CONSENSUS], [COMP-HINF-SIMILAR-TO-CONSENSUS], [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] W [2], [3]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [EXP-IEP-GENE-EXPRESSION-ANALYSIS] Gene expression analysis

 [EXP-IGI] Inferred from genetic interaction

 [COMP-AINF-SIMILAR-TO-CONSENSUS] Automated inference based on similarity to consensus sequences

 [COMP-HINF-SIMILAR-TO-CONSENSUS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS] Binding of purified proteins


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Bernal-Cabas M., Ayala JA., Raivio TL., 2015, The Cpx Envelope Stress Response Modifies Peptidoglycan Cross-Linking via the l,d-Transpeptidase LdtD and the Novel Protein YgaU., J Bacteriol 197(3):603-14

 [3] Raivio TL., Leblanc SK., Price NL., 2013, The Escherichia coli Cpx envelope stress response regulates genes of diverse function that impact antibiotic resistance and membrane integrity., J Bacteriol 195(12):2755-67

RegulonDB