RegulonDB RegulonDB 10.8: Operon Form
   

dinD operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: dinD
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: dinD
Gene(s): dinD   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: dinDp
+1: 3817699
Distance from start of the gene: 61
Sequence: ctgctccagattttgcgatgtttttttgcccagcacactgagaacgtgagatactcacaaCtgtatataaatacagttaca
Evidence: [IHBCE]
[TIM]
Reference(s): [1] Poulsen P., et al., 1989
TF binding sites (TFBSs)
[LexA,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal LexA repressor dinDp 3817697 3817716 8.5 agatactcacAACTGTATATAAATACAGTTacagatttac nd [AIBSCS], [APIORCISFBSCS], [CV(GEA)], [GEA] [2], [3], [4], [5], [6]


Evidence    

 [IHBCE] Inferred by a human based on computational evidence

 [TIM] Transcription initiation mapping

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [CV(GEA)] cross validation(GEA)

 [GEA] Gene expression analysis


Reference(s)    

 [1] Poulsen P., Andersen JT., Jensen KF., 1989, Molecular and mutational analysis of three genes preceding pyrE on the Escherichia coli chromosome., Mol Microbiol 3(3):393-404

 [2] Fernandez De Henestrosa AR., Ogi T., Aoyagi S., Chafin D., Hayes JJ., Ohmori H., Woodgate R., 2000, Identification of additional genes belonging to the LexA regulon in Escherichia coli., Mol Microbiol 35(6):1560-72

 [3] Kaleta C., Gohler A., Schuster S., Jahreis K., Guthke R., Nikolajewa S., 2010, Integrative inference of gene-regulatory networks in Escherichia coli using information theoretic concepts and sequence analysis., BMC Syst Biol 4:116

 [4] Lewis LK., Harlow GR., Gregg-Jolly LA., Mount DW., 1994, Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli., J Mol Biol 241(4):507-23

 [5] Ohmori H., Saito M., Yasuda T., Nagata T., Fujii T., Wachi M., Nagai K., 1995, The pcsA gene is identical to dinD in Escherichia coli., J Bacteriol 177(1):156-65

 [6] Wade JT., Reppas NB., Church GM., Struhl K., 2005, Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites., Genes Dev 19(21):2619-30

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