RegulonDB RegulonDB 10.9: Operon Form
   

fadH operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: fadH
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: fadH
Gene(s): fadH   Genome Browser M3D Gene expression COLOMBOS
Note(s): Repression of fadH transcription by the ArcAB system is additive to FadR repression under anaerobic conditions Feng Y,2010
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: fadHp
+1: 3231624
Distance from start of the gene: 41
Sequence: ccatcacaaaccccgcactccccttttcccttttctccggcgacggctaaattagaactcAtccgaccacataacaattat
Note(s): The CRP-cAMP complex activates the fadH promoter; however, the absence of CRP-cAMP reduces the repression of fadH expression by FadR and ArcA-ArcB. This suggests that HipB may regulate fadH expression in cooperation with other DNA-binding proteins Lin CY,2013
Evidence: [TIM]
Reference(s): [1] Feng Y., et al., 2010
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal ArcA-Phosphorylated repressor fadHp 3231635 3231649 19.0 tccgaccacaTAACAATTATTTTACAtactggacaa nd [EME], [AIBSPD], [APIORCISFBSCS], [CCE], [GEA] [1], [3], [4]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal CRP-cAMP activator fadHp 3231552 3231573 -61.5 ccgggcgtatTCTTTTTGAATCCCATCACAAACcccgcactcc nd [APIORCISFBSCS], [GEA] [1]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal FadR repressor fadHp 3231619 3231635 4.0 gctaaattagAACTCATCCGACCACATAacaattattt nd [APIORCISFBSCS], [BPP], [GEA] [1]
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote HipB repressor fadHp 3231474 3231510 -132.5 gtggacgcctTATCCGCCCTACATGTGCAATTCCGTAACCTGGATAAaacgcgacaa nd [APIORCISFBSCS], [BPP], [GEA] [2]





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