RegulonDB RegulonDB 10.8: Operon Form
   

folE-yeiB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: folE-yeiB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: folE-yeiB
Gene(s): yeiB, folE   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: folEp
+1: 2243848
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 196
Sequence: cgtggctccttgttgtgttgtttgcaatttcttcatcataccgtttattcaatgtgctgtGagtaactttcacttccgtat
                      -35                     -10           +1                   
Evidence: [ICA]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
[MetJ-S-adenosylmethionine,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote MetJ-S-adenosylmethionine repressor folEp 2243792 2243807 49.5 atgttttaacATCTGCTGATGAAAGGcagcggcaat nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [2]
remote MetJ-S-adenosylmethionine repressor folEp 2243800 2243815 41.5 gcataacgatGTTTTAACATCTGCTGatgaaaggca nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [2]
remote MetJ-S-adenosylmethionine repressor folEp 2243808 2243823 33.5 ccgtatttgcATAACGATGTTTTAACatctgctgat nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [2]
proximal MetJ-S-adenosylmethionine repressor folEp 2243816 2243831 25.5 tttcacttccGTATTTGCATAACGATgttttaacat nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [2]


Evidence    

 [ICA] Inferred by computational analysis

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [BPP] Binding of purified proteins

 [CV(GEA)] cross validation(GEA)

 [GEA] Gene expression analysis


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Marincs F., Manfield IW., Stead JA., McDowall KJ., Stockley PG., 2006, Transcript analysis reveals an extended regulon and the importance of protein-protein co-operativity for the Escherichia coli methionine repressor., Biochem J 396(2):227-34

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