RegulonDB RegulonDB 10.6.3: Operon Form
   

ydiV operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: ydiV
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Gene(s): ydiV   Genome Browser M3D Gene expression COLOMBOS
Note(s): The EAL domain protein encoded by ydiV is involved in the interaction between quorum-sensing system 1 (QS system 1) and QS system 2. QS system 1 consists of SdiA responding to signals generated by other microbial species, and QS system 2 is stimulated by the cyclic AMP (cAMP)-cAMP receptor protein (CRP protein) |CITS:[18560382]|.
Expression of sdiA and ydiV is inhibited by glucose. The effect of glucose on ydiV expression is not mediated by SdiA |CITS:[18560382]|.
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: ydiVp
+1: 1792087
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 67
Sequence: aaaggacccctgaaaaagtggttaacatggaacaaatgaaagttactccttctgtaattgTtatgtcttatggcctcatcc
                              -10                    -35    +1                   
Evidence: [AIPP]
Reference(s): [1] Gama-Castro S., et al., 2008
TF binding sites (TFBSs)
[SdiA,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal SdiA activator ydiVp 1792132 1792149 -53.0 gataatctaaAAAAAGGACCCCTGAAAAagtggttaac nd [AIBSCS], [BPP], [GEA] [2]


Evidence    

 [AIPP] Automated inference of promoter position

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [BPP] Binding of purified proteins

 [GEA] Gene expression analysis


Reference(s)    

 [1] Gama-Castro S., Jimenez-Jacinto V., Peralta-Gil M., Santos-Zavaleta A., Penaloza-Spinola MI., Contreras-Moreira B., Segura-Salazar J., Muniz-Rascado L., Martinez-Flores I., Salgado H., Bonavides-Martinez C., Abreu-Goodger C., Rodriguez-Penagos C., Miranda-Rios J., Morett E., Merino E., Huerta AM., Trevino-Quintanilla L., Collado-Vides J., 2008, RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation., Nucleic Acids Res 36(Database issue):D120-4

 [2] Zhou X., Meng X., Sun B., 2008, An EAL domain protein and cyclic AMP contribute to the interaction between the two quorum sensing systems in Escherichia coli., Cell Res 18(9):937-48

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