RegulonDB RegulonDB 10.8: Operon Form
   

ydiV operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: ydiV
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: ydiV
Gene(s): ydiV   Genome Browser M3D Gene expression COLOMBOS
Note(s): The EAL domain protein encoded by ydiV is involved in the interaction between quorum-sensing system 1 (QS system 1) and QS system 2. QS system 1 consists of SdiA responding to signals generated by other microbial species, and QS system 2 is stimulated by the cyclic AMP (cAMP)-cAMP receptor protein (CRP protein) Zhou X,2008
Expression of sdiA and ydiV is inhibited by glucose. The effect of glucose on ydiV expression is not mediated by SdiA Zhou X,2008
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: ydiVp
+1: 1792087
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 67
Sequence: aaaggacccctgaaaaagtggttaacatggaacaaatgaaagttactccttctgtaattgTtatgtcttatggcctcatcc
                              -35                    -10    +1                   
Evidence: [AIPP]
Reference(s): [1] Gama-Castro S., et al., 2008
TF binding sites (TFBSs)
[SdiA,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal SdiA activator ydiVp 1792132 1792149 -53.0 gataatctaaAAAAAGGACCCCTGAAAAagtggttaac nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [2]


Evidence    

 [AIPP] Automated inference of promoter position

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [BPP] Binding of purified proteins

 [CV(GEA)] cross validation(GEA)

 [GEA] Gene expression analysis


Reference(s)    

 [1] Gama-Castro S., Jimenez-Jacinto V., Peralta-Gil M., Santos-Zavaleta A., Penaloza-Spinola MI., Contreras-Moreira B., Segura-Salazar J., Muniz-Rascado L., Martinez-Flores I., Salgado H., Bonavides-Martinez C., Abreu-Goodger C., Rodriguez-Penagos C., Miranda-Rios J., Morett E., Merino E., Huerta AM., Trevino-Quintanilla L., Collado-Vides J., 2008, RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation., Nucleic Acids Res 36(Database issue):D120-4

 [2] Zhou X., Meng X., Sun B., 2008, An EAL domain protein and cyclic AMP contribute to the interaction between the two quorum sensing systems in Escherichia coli., Cell Res 18(9):937-48

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