RegulonDB RegulonDB 10.8: Operon Form

leuE operon and associated TUs in Escherichia coli K-12 genome

Name: leuE
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit          
Name: leuE
Gene(s): leuE   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Name: leuEp
+1: 1880800
Distance from start of the gene: 41
Evidence: [CV(RS-EPT-CBR)]
Reference(s): [1] Kutukova EA., et al., 2005
[2] Salgado H, et al., 2012
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote Lrp-leucine repressor leuEp 1880764 1880775 31.5 atcgaaagatAATTAAAGAGGTtaatgtgttc nd [AIBSCS] [3]
proximal Lrp-leucine repressor leuEp 1880801 1880812 -6.5 acagattggtTAGCATATTCACctttaatcgc nd [AIBSCS] [3]
proximal Lrp-leucine repressor leuEp 1880835 1880846 -40.5 ggttaaaaccTGATTTTCTCCTttctaagccg nd [AIBSCS] [3]
proximal Lrp-leucine repressor leuEp 1880868 1880879 -73.5 ctgattaatgATTCAATTATCGggttgatatc nd [AIBSCS] [3]

RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -6.3 1880838 1880859 cgggttgataTCAGGTTAAAACCTGATTTTCtcctttctaa
  anti-terminator -10.0 1880854 1880891 actggagcatGCCTGATTAATGATTCAATTATCGGGTTGATATCAGGttaaaacctg
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"