RegulonDB RegulonDB 10.8: Operon Form
   

mdtJI operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: mdtJI
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: mdtJI
Gene(s): mdtI, mdtJ   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: mdtJp
+1: 1673779
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 278
Sequence: cgctcaggtaaagaagtgaaaatattttgagttaattcttaagctatgatacaaatcaggCgtgttcaactaccgaggaca
                           -35                  -10         +1                   
Evidence: [TIM]
Reference(s): [1] Leuzzi A., et al., 2015
TF binding sites (TFBSs)
[H-NS,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote H-NS repressor mdtJp 1673487 1673497 288.5 aggacaatgtATATTTATTGGattttattag nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1]
remote H-NS repressor mdtJp 1673535 1673545 240.5 tggtttcgctGAATTAAGCGAaaattaaaat nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1]
proximal H-NS repressor mdtJp 1673785 1673795 -10.5 attcttaagcTATGATACAAAtcaggcgtgt nd [AIBSCS], [BPP], [CV(GEA)], [CV(GEA)], [GEA] [1]


Evidence    

 [TIM] Transcription initiation mapping

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [BPP] Binding of purified proteins

 [CV(GEA)] cross validation(GEA)

 [GEA] Gene expression analysis


Reference(s)    

 [1] Leuzzi A., Di Martino ML., Campilongo R., Falconi M., Barbagallo M., Marcocci L., Pietrangeli P., Casalino M., Grossi M., Micheli G., Colonna B., Prosseda G., 2015, Multifactor Regulation of the MdtJI Polyamine Transporter in Shigella., PLoS One 10(8):e0136744

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