RegulonDB RegulonDB 10.8: Operon Form
   

grxB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: grxB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: grxB
Gene(s): grxB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: grxBp
+1: 1124103
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 49
Sequence: tagccagaaacgcgccgcgcgtcgtttgcttgaacgcgacgcctgatttgatactcccccCtgactccttcatactgaaag
                          -35                     -10       +1                   
Evidence: [AIPP]
Reference(s): [1] Huerta AM., et al., 2003
Allosteric regulation of RNA-polymerase
  Regulator Function Promoter target of RNApol Growth Conditions Note Evidence Reference
  ppGpp activation grxBp ppGpp regulates the expression of the grxB gene together with σS and σ70 during the exponential and stationary phases, respectively 11889138 [GEA]
[IMP] 		[2]
Evidence: [GEA] Gene expression analysis
[IMP] Inferred from mutant phenotype
Reference(s): [2] Klein RZ., et al., 1991


Evidence    

 [AIPP] Automated inference of promoter position


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Klein RZ., Haddow JE., Faix JD., Brown RS., Hermos RJ., Pulkkinen A., Mitchell ML., 1991, Prevalence of thyroid deficiency in pregnant women., Clin Endocrinol (Oxf) 35(1):41-6

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