RegulonDB RegulonDB 10.7: Operon Form

pflA operon and associated TUs in Escherichia coli K-12 genome

Name: pflA
This page displays every known transcription unit of this operon and their known regulation.

Transcription unit       
Name: pflA
Gene(s): pflA   Genome Browser M3D Gene expression COLOMBOS
Note(s): The expression of the gene pflA is increased under acidic growth conditions in microaerobiosis |CITS:[23274360]|. The increased expression of this gene is in agreement with the increased formate production observed under acidic conditions |CITS:[23274360]|.
Evidence: [ICWHO] Inferred computationally without human oversight
[LTED] Length of transcript experimentally determined
Reference(s): [1] Sauter M., et al., 1990
Name: pflAp
+1: 951154
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 74
Sequence: gggccttttttagcgcgagagccttttttgtcagctatctatactttaaggtgactgccaAaacagactcgacgtagcctt
                            -35              -10            +1                   
Evidence: [TIM]
Reference(s): [1] Sauter M., et al., 1990
Type: rho-independent
Reference(s): [1] Sauter M., et al., 1990

Regulation by sRNA    
  Small RNA name (Regulator) Regulation type Mechanism Function Binding Sites Evidence Reference
LeftPos RightPos Sequence (RNA-strand)
  ryhB antisense post-transcriptional regulation repressor       [IMP] [2]
Notes: "The provided sequence is that of the RNA strand,i.e. 'U's are showed instead the 'T'"

RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
Evidence: [ICA] Inferred by computational analysis
Reference(s): [3] Merino E, et al., 2005
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -19.1 951203 951230 cgtacaataaAGGCTCCACGAAAGTGGGGCCTTTTTTagcgcgagag
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"