RegulonDB RegulonDB 10.8: Operon Form
   

argS operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: argS
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: argS
Gene(s): argS   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
[LTED] Length of transcript experimentally determined
Reference(s): [1] Eriani G., et al., 1989
Promoter
Name: argSp
+1: 1960001
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 61
Sequence: aaacggcaatacgccacgcgcacgttgctgacgaaaacagccatttgcagtatactcccgCcctaatttctttaactggtg
                         -35                       -10      +1                   
Note(s): Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: high homology. Score: 4.434. P-value: 1.086e-5
Evidence: [ICWHO]
[TIM]
Reference(s): [1] Eriani G., et al., 1989
[2] Huerta AM., et al., 2003
Terminator(s)
Type: rho-independent
Sequence: tgagagtgaaGCCTGATCAGGGTTAGCCGATCAGGCTtttttattgc
Reference(s): [1] Eriani G., et al., 1989
Allosteric regulation of RNA-polymerase
  Regulator Function Promoter target of RNApol Growth Conditions Note Evidence Reference
  ppGpp inhibition argSp   [GEA] [3]
Evidence: [GEA] Gene expression analysis
Reference(s): [3] Traxler MF., et al., 2008


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: forward
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -10.34 1959997 1960034 cagtatactcCCGCCCTAATTTCTTTAACTGGTGCGGGCAATTTTTGctcgcttcat
  anti-terminator -8.7 1959958 1960001 atacgccacgCGCACGTTGCTGACGAAAACAGCCATTTGCAGTATACTCCCGCcctaatttct
  anti-anti-terminator -12.1 1959924 1959975 tcacgccgctTCTGATGCAATAGTGAAAACGGCAATACGCCACGCGCACGTTGCTGACGAAaacagccatt
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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