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| Operon |  |
|---|---|
| Name: | mprA-emrAB |
| This page displays every known transcription unit of this operon and their known regulation. | |
| Name: | emrRAB |
| Gene(s): | mprA, emrA, emrB Genome Browser M3D Gene expression COLOMBOS |
| Note(s): | Hirakawa et al. demonstrated that OmpR increases mRNA expression of the emrA gene by 6.5 times, providing possible evidence that OmpR regulates the expression of its encoding operon, emrRAB Hirakawa H,2003 The expression of the emrB gene, and probably the expression of the whole emrRAB operon, is affected by antibiotic pressure. An increase in emrB expression is maintained during exposition to increasing concentrations of tetracycline 17426813 |
| Evidence: | [PM] Polar mutation |
| Reference(s): | [1] Lomovskaya O., et al., 1995 |
| Promoter | |
| Name: | mprAp |
| +1: | 2810747 |
| Sigma Factor: | Sigma70 Sigmulon |
| Distance from start of the gene: | 23 |
| Sequence: |
gaatcatttttctaaaacaatacatttactttatttgtcactgtcgttactatatcggctGaaattaatgaggtcataccc -35 -10 +1 |
| Evidence: |
[HIPP] [TIM] |
| Reference(s): |
[1] Lomovskaya O., et al., 1995 [2] Xiong A., et al., 2000 |
| RNA cis-regulatory element | |
|---|
| Regulation, transcriptional elongation | |
| Attenuator type: | Transcriptional |
| Strand: | forward |
| Structure type | Energy | LeftPos | RightPos | Sequence (RNA-strand) | |
|---|---|---|---|---|---|
| terminator | -15.5 | 2811348 | 2811377 | aaaatgactgGCCAGCATCGCAACATGCTGGCCTTTTTGgcaagcaggt | |
| anti-terminator | -13.9 | 2811289 | 2811359 | gttctcgaagCGATGAGCTAACGCGTCATCTCGCTCAAAAATCCAGATTTATAAAAGAAAAAATGACTGGCCAGCATCGCaacatgctgg | |
| anti-anti-terminator | -12.54 | 2811278 | 2811324 | aagacggtgtGGTTCTCGAAGCGATGAGCTAACGCGTCATCTCGCTCAAAAATCCAgatttataaa |
| Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos" |
| Reference(s) |
|
|---|---|
[HIPP] Human inference of promoter position