RegulonDB RegulonDB 10.8: Operon Form
   

symE operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: symE
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: symE
Synonym(s): yjiW
Gene(s): symE   Genome Browser M3D Gene expression COLOMBOS
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] Fernandez De Henestrosa AR., et al., 2000
Promoter
Name: symEp
+1: 4579917
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 77
Sequence: ttgcccattttattctatttttagctggactttccccatatttactgatgatatatacagGtatttagcgcggtgcggatg
                                -35                   -10   +1                   
Evidence: [HIPP]
[TAS]
Reference(s): [2] Kawano M., et al., 2007
TF binding sites (TFBSs)
[LexA,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal LexA repressor symEp 4579916 4579935 -8.5 tccccatattTACTGATGATATATACAGGTatttagcgcg nd [AIBSCS], [BPP] [1], [3]


Regulation by sRNA    
  Small RNA name (Regulator) Regulation type Mechanism Function Binding Sites Evidence Reference
LeftPos RightPos Sequence (RNA-strand)
  symR antisense post-transcriptional regulation repressor      
Notes: "The provided sequence is that of the RNA strand,i.e. 'U's are showed instead the 'T'"


Evidence    

 [HIPP] Human inference of promoter position

 [TAS] Traceable author statement

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [BPP] Binding of purified proteins


Reference(s)    

 [1] Fernandez De Henestrosa AR., Ogi T., Aoyagi S., Chafin D., Hayes JJ., Ohmori H., Woodgate R., 2000, Identification of additional genes belonging to the LexA regulon in Escherichia coli., Mol Microbiol 35(6):1560-72

 [2] Kawano M., Aravind L., Storz G., 2007, An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin., Mol Microbiol 64(3):738-54

 [3] Lewis LK., Harlow GR., Gregg-Jolly LA., Mount DW., 1994, Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli., J Mol Biol 241(4):507-23

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