RegulonDB RegulonDB 10.10: Operon Form
   

symE operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: symE
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: symE
Synonym(s): yjiW
Gene(s): symE   Genome Browser M3D Gene expression COLOMBOS
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] Fernandez De Henestrosa AR., et al., 2000
Promoter
Name: symEp
+1: 4579917
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 77
Sequence: ttgcccattttattctatttttagctggactttccccatatttactgatgatatatacagGtatttagcgcggtgcggatg
                                -35                   -10   +1                   
Evidence: [HIPP]
[ICWHO]
[TAS]
Reference(s): [2] Huerta AM., et al., 2003
[3] Kawano M., et al., 2007
TF binding sites (TFBSs)
[LexA,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal LexA repressor symEp 4579916 4579935 -8.5 tccccatattTACTGATGATATATACAGGTatttagcgcg nd [AIBSCS], [BPP] [1]
sRNA Interaction TU
sRNA TU Regulated Function Binding Sites Regulatory Mechanism Evidence (Confirmed, Strong, Weak) Reference(s)
PosLeft PosRight Target sequence (mRNA)
small regulatory RNA antitoxin SymR symE repressor 4579835 4579911 AGUCAUAACUGCUAUUCUCCAGGAAUAGUGAUUGUGAUUAGCGAUGCGGGUGUGUUGGCGCACAUCCGCACCGCGCU MRNA-DEGRADATION [IMP] [3]


Evidence    

 [HIPP] Human inference of promoter position

 [ICWHO] Inferred computationally without human oversight

 [TAS] Traceable author statement

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [BPP] Binding of purified proteins

 [IMP] Inferred from mutant phenotype


Reference(s)    

 [1] Fernandez De Henestrosa AR., Ogi T., Aoyagi S., Chafin D., Hayes JJ., Ohmori H., Woodgate R., 2000, Identification of additional genes belonging to the LexA regulon in Escherichia coli., Mol Microbiol 35(6):1560-72

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Kawano M., Aravind L., Storz G., 2007, An antisense RNA controls synthesis of an SOS-induced toxin evolved from an antitoxin., Mol Microbiol 64(3):738-54

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