RegulonDB RegulonDB 10.8: Operon Form
   

yeiR-lpxT operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: yeiR-lpxT
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: lpxT
Gene(s): lpxT   Genome Browser M3D Gene expression COLOMBOS
Note(s): The lpxT transcript is more abundant and stable at low temperatures (28 o C) than at 37-42 o C Sciandrone B,2019. The RNase E appears to degrade the transcript at high temperatures.
In Salmonella, the transcription of lpxT is induced by PhoP at low Mg2+ concentrations 29739882.
Evidence: [IEP] Inferred from expression pattern
[LTED] Length of transcript experimentally determined
Reference(s): [1] Li Z., et al., 2019
[2] Sciandrone B., et al., 2019
Promoter
Name: lpxTp
+1: 2268826
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 28
Sequence: atgccttgcagagcgcgctgttgaagcttcgtttagcgactaccgcgtaaggttgcctgcGtttttcagtaagataattag
                                                -10         +1                   
Note(s): The lpxTp promoter is active in exponential phase and at low temperatures, and it is inactive during stationary phase Sciandrone B,2019.
Evidence: [RE]
[TIM]
Reference(s): [1] Li Z., et al., 2019
[2] Sciandrone B., et al., 2019


Transcription unit       
Gene(s): yeiR, lpxT   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight


Evidence    

 [RE] RNA-seq evidence

 [TIM] Transcription initiation mapping


Reference(s)    

 [1] Li Z., Pan Q., Xiao Y., Fang X., Shi R., Fu C., Danchin A., You C., 2019, Deciphering global gene expression and regulation strategy in Escherichia coli during carbon limitation., Microb Biotechnol 12(2):360-376

 [2] Sciandrone B., Forti F., Perego S., Falchi F., Briani F., 2019, Temperature-dependent regulation of the Escherichia coli lpxT gene., Biochim Biophys Acta Gene Regul Mech 1862(8):786-795

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