RegulonDB RegulonDB 10.8: Operon Form
   

menFDHBCE operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: menFDHBCE
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: menFD-yfbB-menBCE
Gene(s): menE, menC, menB, menH, menD, menF   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for menF . This structure could regulate the expression of the gene, as observed for hemL gene expression 31964733.
Reference(s): [1] Sharma V., et al., 1996


Transcription unit       
Name: menD-yfbB-menBCE
Gene(s): menE, menC, menB, menH, menD   Genome Browser M3D Gene expression COLOMBOS
Promoter
Name: menDp
+1: Unknown
Note(s): Zaslaver et al. demonstrated in 2006, by means of a library of fluorescent transcription fusions, that this promoter can be transcribed in vitro Zaslaver A,2006. Based on this, a putative promoter was suggested, but the +1 site of the transcription initiation has not been determined, although there exists promoter activity.
Evidence: [IEP]
Reference(s): [2] Zaslaver A., et al., 2006


Transcription unit       
Name: menBCE
Gene(s): menE, menC, menB   Genome Browser M3D Gene expression COLOMBOS
Note(s): There is an overlap among the menBCE genes.
Reference(s): [3] Sharma V., et al., 1992


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -9.0 2380642 2380673 accccgtataATGTGAGGCTTTTAACAGGGAGAGGTCCGCGtgcaatcact
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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