RegulonDB RegulonDB 10.8: Operon Form
   

dapA-bamC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: dapA-bamC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: bamC
Synonym(s): nlpB
Gene(s): bamC   Genome Browser M3D Gene expression COLOMBOS
Note(s): A potential RNA G-quadruplex structure, formed by guanine-rich sequences located in the coding sequence region of the gene, was identified for bamC . This structure could regulate the expression of the gene, as observed for hemL gene expression 31964733.
Evidence: [BTEI] Boundaries of transcription experimentally identified
Reference(s): [1] Bouvier J., et al., 1991
[2] Dartigalongue C., et al., 2001
Promoter
Name: bamCp
+1: 2599014
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 149
Sequence: acgcgttattaatcagcgtctgatgccattacacaacaaactatttgtcgaacccaatccAatcccggtgaaatgggcatg
                         -35                    -10         +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [2] Dartigalongue C., et al., 2001
Terminator(s)
Type: rho-independent
Sequence: atcagaaaaaAGGGCCGGATGATTCCAGCCCTgtatttttac
Reference(s): [1] Bouvier J., et al., 1991


Transcription unit       
Name: dapA-nlpB
Gene(s): bamC, dapA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [PM] Polar mutation
Reference(s): [1] Bouvier J., et al., 1991
Promoter
Name: dapAp
+1: 2599784
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 24
Sequence: aacaatcagaacggttctgtctgcttgcttttaatgccataccaaacgtaccattgagacActtgtttgcacagaggatgg
                         -35                     -10        +1                   
Note(s): While lysine and the growth rate do not affect the dapAp promoter, the metabolite diaminopimelic acid regulates this promoter negatively. However, it is not known if this regulation is direct or through a transcription factor Jovanovic M,2003
Evidence: [CV(RS-EPT-CBR)]
[CV(TIM)]
[HIPP]
[RS-EPT-CBR]
[TIM]
Reference(s): [3] Richaud F., et al., 1986
[4] Salgado H, et al., 2012
Terminator(s)
Type: rho-independent
Sequence: atcagaaaaaAGGGCCGGATGATTCCAGCCCTgtatttttac
Reference(s): [1] Bouvier J., et al., 1991





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