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Name: | murR |
Gene(s): | murR Genome Browser M3D Gene expression COLOMBOS |
Note(s): | murR and murQ are divergently orientated and expressed from nonoverlapping face-to-face (convergent) promoters, and their transcripts are complementary at the 5' end. CRP controls positively murQP expression and it also may affect murR transcription as a consequence of this unusual promoter arrangement (face-to-face) Jaeger T,2008 CRP and MurR both repress murR expression beyond transcription initiation, possibly by generating a roadblock for RNA polymerase Jaeger T,2008 Autoinduction of murR is carried out by an activated form of MurR, which may be an activator form after interaction with an as yet unidentified effector, possibly a IIBC component, since most phosphorylated sugars can trigger activation of murR in a MurR-dependent manner Ishii D,2009 |
Evidence: | [ICWHO] Inferred computationally without human oversight |
Promoter | |
Name: | murRp |
+1: | 2545793 |
Sigma Factor: | Sigma70, Sigma38 |
Distance from start of the gene: | 184 |
Sequence: |
gcacatttccagcgtcgatacgcggtcaatttcagccgaggcggtgttcgagccttcagtAatcatcttttcaaattgcat -35 -10 +1 |
Evidence: | [TIM] |
Reference(s): | [1] Jaeger T., et al., 2008 |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | MurR | activator | murRp | 2545911 | 2545925 | -125.0 | taacatcgatCGCCGCGGCGATATCcggcagtacg | nd | [APIORCISFBSCS], [CV(GEA)], [GEA] | [2] |
Type | Transcription factor | Function | Promoter | Binding Sites | Growth Conditions | Evidence (Confirmed, Strong, Weak) | Reference(s) | |||
---|---|---|---|---|---|---|---|---|---|---|
LeftPos | RightPos | Central Rel-Pos | Sequence | |||||||
remote | MurR | repressor | murRp | 2545911 | 2545925 | -125.0 | taacatcgatCGCCGCGGCGATATCcggcagtacg | nd | [APIORCISFBSCS], [CV(GEA)], [GEA] | [2] |
Reference(s) |
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