RegulonDB RegulonDB 10.7: Operon Form
   

ycgZ-ymgA-ariR-ymgC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: ycgZ-ymgA-ariR-ymgC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: ycgZ-ymgA-ariR-ymgC
Gene(s): ycgZ, ymgA, ariR, ymgC   Genome Browser M3D Gene expression COLOMBOS
Note(s): ycgZ-ymgA-ariR-ymgC constitutes an operon. YmgA and AriR activate production of the biofilm matrix substance colanic acid as well as acid resistance genes and the biofilm-associated bdm gene and they downregulate adhesive curli fimbriae |CITS:[17222132][17609140][17765265][19172264]|. YcgZ appears to counteract the activities of YmgA and YmgB |CITS:[19240136]|.
Expression of this operon is under the control of σ38 (rpoS) RNA polymerase and repressed by ycgE, which is transcribed divergently on the opposite strand |CITS:[19240136][ 15716429]|.
Evidence: [LTED] Length of transcript experimentally determined
[LTED] Length of transcript experimentally determined
Reference(s): [1] Tschowri N., et al., 2009
Promoter
Name: ycgZp
+1: 1215752
Sigma Factor: Sigma38, Sigma70
Distance from start of the gene: 37
Sequence: gcaaaaaattaatttatcattctgtacacatatttcgtacaagtttgctattgttacttcActtaacattgattaacattt
                         -35                -10             +1                   
Evidence: [HIPP]
[TIM]
Reference(s): [2] Gama-Castro S., et al., 2008
[3] Tschowri N., et al., 2012
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal BluR repressor ycgZp 1215713 1215733 -29.5 atttatcattCTGTACACATATTTCGTACAAgtttgctatt nd [BPP], [GEA], [SM] [1], [3]


Transcription unit       
Gene(s): ymgC   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight


Transcription unit       
Gene(s): ymgA, ariR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight


Transcription unit       
Gene(s): ycgZ   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight


Transcription unit       





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