RegulonDB RegulonDB 10.8: Operon Form
   

glrR-glnB operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: glrR-glnB
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: glnB
Gene(s): glnB   Genome Browser M3D Gene expression COLOMBOS
Note(s): The expression of the glnB gene was increased in mutants for two genes that encode two terminal oxidases, cyoA and cydB, and in mutants of two transcriptional regulators, Fnr and Fur. However, it is unknown if the effects of the transcriptional regulators act directly on the gene expression; also, it is unknown which of the three promoters that transcribe the gene could be regulated by the regulators Kumar R,2011
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] He B., et al., 1993
Promoter
Name: glnBp1
+1: 2687441
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 33
Sequence: cacgagctggatgcaaacgatttcaaggaatgaattggcgttatgtgttacgtttagcagAtcaaaagacaggcgaccttt
                      -35                        -10        +1                   
Evidence: [TIM]
Reference(s): [1] He B., et al., 1993
[2] van Heeswijk WC., et al., 1993
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal PurR-hypoxanthine1 repressor glnBp1 2687476 2687491 -42.5 cacgagctggATGCAAACGATTTCAAggaatgaatt nd [APIORCISFBSCS], [BCE], [CV(GEA)], [GEA] [1]
Note(s): 1We have assumed that PurR negatively regulates these two promoters, but in the paper of He et al., 1993, this was not clear He B,1993|.1We have assumed that PurR negatively regulates these two promoters, but in the paper of He et al., 1993, this was not clear He B,1993|.


Transcription unit          
Name: glnB
Synonym(s): OP00126
Gene(s): glnB   Genome Browser M3D Gene expression COLOMBOS
Note(s): The expression of the glnB gene was increased in mutants for two genes that encode two terminal oxidases, cyoA and cydB, and in mutants of two transcriptional regulators, Fnr and Fur. However, it is unknown if the effects of the transcriptional regulators act directly on the gene expression; also, it is unknown which of the three promoters that transcribe the gene could be regulated by the regulators Kumar R,2011
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] He B., et al., 1993
[3] Liu J., et al., 1993
Promoter
Name: glnBp2
+1: 2687503
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 95
Sequence: tcacccacgcggcgagaatggcggggcgcaaccggacagaattttataaactgctttcccGacacgagctggatgcaaacg
                       -35                     -10          +1                   
Evidence: [TIM]
Reference(s): [1] He B., et al., 1993
[3] Liu J., et al., 1993
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal PurR-hypoxanthine1 repressor glnBp2 2687476 2687491 20.5 cacgagctggATGCAAACGATTTCAAggaatgaatt nd [APIORCISFBSCS], [BCE], [CV(GEA)], [GEA] [1]
Note(s): 1We have assumed that PurR negatively regulates these two promoters, but in the paper of He et al., 1993, this was not clear He B,1993|.1We have assumed that PurR negatively regulates these two promoters, but in the paper of He et al., 1993, this was not clear He B,1993|.


Transcription unit       
Name: glnB
Gene(s): glnB   Genome Browser M3D Gene expression COLOMBOS
Note(s): The expression of the glnB gene was increased in mutants for two genes that encode two terminal oxidases, cyoA and cydB, and in mutants of two transcriptional regulators, Fnr and Fur. However, it is unknown if the effects of the transcriptional regulators act directly on the gene expression; also, it is unknown which of the three promoters that transcribe the gene could be regulated by the regulators Kumar R,2011
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [1] He B., et al., 1993
Promoter
Name: glnBp3
+1: 2687526
Distance from start of the gene: 118
Sequence: gctgcaaatcaccaaaggcaacgtcacccacgcggcgagaatggcggggcgcaaccggacAgaattttataaactgctttc
Evidence: [TIM]
Reference(s): [1] He B., et al., 1993


Transcription unit       
Name: glrR-glnB
Gene(s): glnB, glrR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [LTED] Length of transcript experimentally determined
Reference(s): [2] van Heeswijk WC., et al., 1993


Transcription unit       
Name: yfhA
Gene(s): glrR   Genome Browser M3D Gene expression COLOMBOS
Evidence: [IHBCE] Inferred by a human based on computational evidence





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