RegulonDB RegulonDB 10.10: Operon Form
   

bdcA operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: bdcA
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: bdcA
Gene(s): bdcA   Genome Browser M3D Gene expression COLOMBOS
Note(s): Based on transcription analysis with qRT-PCR and mutants, it was shown that BdcR (formerly YjgJ) is a negative regulator of the bdcA gene Ma Q,2011
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: bdcAp
+1: 4474064
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 11
Sequence: ttacaaaacctgttgacagaaagttaaaacagttttgtaatgcatgttacataataaatcAaggagtccttatgggcgctt
                        -35                       -10       +1                   
Evidence: [AIPP]
[ICWHO]
Reference(s): [1] Huerta AM., et al., 2003
TF binding sites (TFBSs)
[NsrR,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal NsrR repressor bdcAp 4474077 4474088 -18.0 aaacagttttGTAATGCATGTTacataataaa nd [GEA], [APIORCISFBSCS] [2]


Evidence    

 [AIPP] Automated inference of promoter position

 [ICWHO] Inferred computationally without human oversight

 [GEA] Gene expression analysis

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Partridge JD., Bodenmiller DM., Humphrys MS., Spiro S., 2009, NsrR targets in the Escherichia coli genome: new insights into DNA sequence requirements for binding and a role for NsrR in the regulation of motility., Mol Microbiol 73(4):680-94

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