RegulonDB RegulonDB 11.1: Operon Form
   

prlF-yhaV operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: prlF-yhaV
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: sohA-yhaV
Gene(s): prlF, yhaV   Genome Browser M3D Gene expression COLOMBOS
Evidence: [COMP-AINF] Inferred computationally without human oversight
[EXP-IEP-COREGULATION] Inferred through co-regulation
[EXP-IMP-POLAR-MUTATION] Polar mutation
[IC-ADJ-GENES-SAME-BIO-PROCESS] Products of adjacent genes in the same biological process
Reference(s): [1] Schmidt O., et al., 2007
Promoter
Name: sohAp
+1: 3276972
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 30
Sequence: agcccccacgtccattaataatgcatttgcattaccttagttcaagcttataatttgagcAgaaaacaggctgtaaaagga
                           -35                   -10        +1                   
Evidence: [COMP-AINF]
[COMP-HINF-POSITIONAL-IDENTIFICATION]
[RS-EPT-CBR]
Reference(s): [2] Huerta AM., et al., 2003
[3] Kiino DR., et al., 1990
[4] Salgado H, et al., 2012


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [COMP-HINF-POSITIONAL-IDENTIFICATION] Human inference of promoter position

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Schmidt O., Schuenemann VJ., Hand NJ., Silhavy TJ., Martin J., Lupas AN., Djuranovic S., 2007, prlF and yhaV Encode a New Toxin-Antitoxin System in Escherichia coli., J Mol Biol 372(4):894-905

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Kiino DR., Phillips GJ., Silhavy TJ., 1990, Increased expression of the bifunctional protein PrlF suppresses overproduction lethality associated with exported beta-galactosidase hybrid proteins in Escherichia coli., J Bacteriol 172(1):185-92

 [4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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