RegulonDB RegulonDB 10.7: Operon Form
   

mntP operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: mntP
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Gene(s): mntP   Genome Browser M3D Gene expression COLOMBOS
Note(s): The reciprocal expression of mntP and mntS suggests negative regulation of mntP by the mntS transcript |CITS:[21908668]|.
Evidence: [ICWHO] Inferred computationally without human oversight
[LTED] Length of transcript experimentally determined
Reference(s): [1] Waters LS., et al., 2011
Promoter
Name: mntPp
+1: 1905459
Sigma Factor: Sigma70 Sigmulon
Distance from start of the gene: 229
Sequence: aagcaatgaaataatatattccaacagttgttttatattctcaaaatatgttaaggttgcGccctcatttggggagtagcc
                            -35                -10          +1                   
Evidence: [TIM]
Reference(s): [1] Waters LS., et al., 2011
TF binding sites (TFBSs)
[Fur,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
proximal Fur-Fe2+ activator mntPp 1905378 1905398 -71.5 atataaatccAAATGAAAATCGTTATCAATAaagcaatgaa nd [AIBSCS] [1]
[MntR,+] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote MntR-Mn2+ activator mntPp 1905265 1905286 -183.5 aataagttatGAATTTAGCCAAAGCTATGTTTagtgtatttt nd [APIORCISFBSCS], [GEA] [1]
remote MntR-Mn2+ activator mntPp 1905305 1905326 -143.5 tttaataatcAGACATAGCTTAGGCTATATTAcctcttccct nd [APIORCISFBSCS], [GEA] [1]


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Translational
Strand: forward
Evidence: [ICA] Inferred by computational analysis
Reference(s): [2] Merino E, et al., 2005
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -9.6 1905641 1905674 gcatgtttgcTGGGGGCGATGATGTGTTTTATGGATACCCCGGtcaggacatt
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"


Evidence    

 [TIM] Transcription initiation mapping

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [APIORCISFBSCS] A person inferred or reviewed a computer inference of sequence function based on similarity to a consensus sequence.

 [GEA] Gene expression analysis


Reference(s)    

 [1] Waters LS., Sandoval M., Storz G., 2011, The Escherichia coli MntR miniregulon includes genes encoding a small protein and an efflux pump required for manganese homeostasis., J Bacteriol 193(21):5887-97

 [2] Merino E, Yanofsky C., 2005, Transcription attenuation: a highly conserved regulatory strategy used by bacteria., Trends Genet. 2005 May;21(5):260-4.

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