RegulonDB RegulonDB 10.10: Operon Form
   

psd-mscM operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: psd-mscM
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: psd-mscM
Gene(s): mscM, psd   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: psdp
+1: 4390638
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 278
Sequence: gtgagttcggcctctggcacctggagccggaacaaatcactcagggctttgtcgaattccAtgactatttaggtctgtgta
                              -35                   -10     +1                   
Note(s): This promoter appears to be induced during the first 15 minutes following σE induction; after 15 minutes it is drastically decreased Lacoux C,2020
Evidence: [AIBSCS]
[AIPP]
[ICWHO]
[IEP]
[TIM]
Reference(s): [1] Huerta AM., et al., 2003
[2] Lacoux C., et al., 2020
[3] Rezuchova B., et al., 2003
[4] Rhodius VA., et al., 2005
TF binding sites (TFBSs)
[CpxR,-] Phrase
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
remote CpxR-phosphorylated repressor psdp 4390481 4390495 151.0 catggcgcagGTAAAAACGCGTAAAaacttttctg nd [ICA] [5]


Evidence    

 [AIBSCS] Automated inference based on similarity to consensus sequences

 [AIPP] Automated inference of promoter position

 [ICWHO] Inferred computationally without human oversight

 [IEP] Inferred from expression pattern

 [TIM] Transcription initiation mapping

 [ICA] Inferred by computational analysis


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Lacoux C., Fouquier d'Herouel A., Wessner-Le Bohec F., Innocenti N., Bohn C., Kennedy SP., Rochat T., Bonnin RA., Serror P., Aurell E., Bouloc P., Repoila F., 2020, Dynamic insights on transcription initiation and RNA processing during bacterial adaptation., RNA 26(4):382-395

 [3] Rezuchova B., Miticka H., Homerova D., Roberts M., Kormanec J., 2003, New members of the Escherichia coli sigmaE regulon identified by a two-plasmid system., FEMS Microbiol Lett 225(1):1-7

 [4] Rhodius VA., Suh WC., Nonaka G., West J., Gross CA., 2005, Conserved and variable functions of the sigmaE stress response in related genomes., PLoS Biol 4(1):e2

 [5] De Wulf P., McGuire AM., Liu X., Lin EC., 2002, Genome-wide profiling of promoter recognition by the two-component response regulator CpxR-P in Escherichia coli., J Biol Chem 277(29):26652-61

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