RegulonDB RegulonDB 10.8: Operon Form
   

mepS operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: mepS
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit       
Name: mepS
Gene(s): mepS   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: mepSp2
+1: 2269811
Distance from start of the gene: 168
Sequence: ttataaaaaatcatgtaaaaccgctcgccaagaccgcaccaatcgggtaatctcgaactcGttttgcctcggcggtagatt
Note(s): mepS p2 was validated experimentally in aerobic conditions Chung D,2013.
Evidence: [TIM]
Reference(s): [1] Chung D., et al., 2013


Transcription unit       
Name: mepS
Gene(s): mepS   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight
Promoter
Name: mepSp
+1: 2269920
Distance from start of the gene: 59
Sequence: agtccacagatttggccttaaggaattgtttcaacatgcccaggtaattagtctcgtgtcGcttggcatttttttataacg
Note(s): mepSp was validated experimentally in aerobic conditions Chung D,2013.
Evidence: [CV(RS-EPT-CBR)]
[CV(TIM)]
[HTIM]
[RS-EPT-CBR]
[TIM]
Reference(s): [1] Chung D., et al., 2013
[2] Mendoza-Vargas A., et al., 2009
[3] Salgado H, et al., 2012


Evidence    

 [TIM] Transcription initiation mapping

 [CV(RS-EPT-CBR)] cross validation(RS-EPT-CBR)

 [CV(TIM)] cross validation(TIM)

 [HTIM] High-throughput transcription initiation mapping

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Chung D., Park D., Myers K., Grass J., Kiley P., Landick R., Keles S., 2013, dPeak: high resolution identification of transcription factor binding sites from PET and SET ChIP-Seq data., PLoS Comput Biol 9(10):e1003246

 [2] Mendoza-Vargas A., Olvera L., Olvera M., Grande R., Vega-Alvarado L., Taboada B., Jimenez-Jacinto V., Salgado H., Juarez K., Contreras-Moreira B., Huerta AM., Collado-Vides J., Morett E., 2009, Genome-wide identification of transcription start sites, promoters and transcription factor binding sites in E. coli., PLoS One 4(10):e7526

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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