RegulonDB RegulonDB 10.8: Operon Form
   

rclABC operon and associated TUs in Escherichia coli K-12 genome




Operon      
Name: rclABC
This page displays every known transcription unit of this operon and their known regulation.


Transcription unit          
Name: rclABC
Gene(s): rclC, rclB, rclA   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ITC] Inferred through co-regulation
[PAGTSBP] Products of adjacent genes in the same biological process
Reference(s): [1] Parker BW., et al., 2013
Promoter
Name: ykgCp1
+1: 320215
Sigma Factor: Sigma24 Sigmulon
Distance from start of the gene: 214
Sequence: tcgttccttgtggagcgttaagcatcaacaaacggctaagggcatccatatcagactcctGagtggtttttgattacaaac
                         -35                     -10        +1                   
Note(s): Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: -2.31. P-value: 2.000e-5
Evidence: [ICWHO]
Reference(s): [2] Huerta AM., et al., 2003
TF binding sites (TFBSs)
Type Transcription factor Function Promoter Binding Sites Growth Conditions Evidence (Confirmed, Strong, Weak) Reference(s)
LeftPos RightPos Central Rel-Pos Sequence
nd RclR activator ykgCp1 nd nd nd nd nd [BPP], [GEA] [1]


Transcription unit       
Gene(s): rclC, rclB   Genome Browser M3D Gene expression COLOMBOS
Evidence: [ICWHO] Inferred computationally without human oversight


Regulation by sRNA    
  Small RNA name (Regulator) Regulation type Mechanism Function Binding Sites Evidence Reference
LeftPos RightPos Sequence (RNA-strand)
  omrB antisense post-transcriptional regulation activator       [IMP] [3]
[4]
  omrA antisense post-transcriptional regulation activator       [IMP] [3]
[4]
  omrB antisense post-transcriptional regulation activator       [IMP] [3]
[4]
  omrB antisense post-transcriptional regulation activator       [IMP] [3]
[4]
Notes: "The provided sequence is that of the RNA strand,i.e. 'U's are showed instead the 'T'"


RNA cis-regulatory element    
Regulation, transcriptional elongation  
Attenuator type: Transcriptional
Strand: reverse
  Structure type Energy LeftPos RightPos Sequence (RNA-strand)
  terminator -6.1 320204 320230 ctaagggcatCCATATCAGACTCCTGAGTGGTTTTTgattacaaac
  anti-terminator -11.6 320226 320267 gatcgttcctTGTGGAGCGTTAAGCATCAACAAACGGCTAAGGGCATCCATatcagactcc
  anti-anti-terminator -9.5 320269 320302 agctgccagtCACTTCCTAACACGCAATTCTTATCGATCGTTCcttgtggagc
Notes: "The provided "Sequence" is that of the RNA strand, i.e. U's are shown instead of T's and regulators on the reverse strand will appear as the reverse complement of the sequence delimited by LeftPos-RigtPos"





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